PDB entry 1nq2

View 1nq2 on RCSB PDB site
Description: Two RTH Mutants with Impaired Hormone Binding
Class: hormone/growth factor receptor
Keywords: alpha helical, ligand binding domain, hormone-growth factor receptor complex
Deposited on 2003-01-21, released 2003-04-15
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.227
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thyroid hormone receptor Beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: THRB OR NR1A2 OR ERBA2 OR THR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10828 (4-End)
      • cloning artifact (0-3)
      • variant (119)
      • conflict (124)
    Domains in SCOPe 2.01: d1nq2a_
  • Heterogens: NA, 4HY, ARS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nq2A (A:)
asaaeelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqapivn
apeggkvdleafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslrt
avryepesetltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavl
lmssdrpglacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachas
rflhmkvecptelfpplflevfed

    Sequence, based on observed residues (ATOM records): (download) 
    >1nq2A (A:)
asaaeelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqagkvd
leafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslrtavryepes
etltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmssdrpg
lacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflhmkve
cptelfpplflevfe