PDB entry 1np0

View 1np0 on RCSB PDB site
Description: human lysosomal beta-hexosaminidase isoform b in complex with intermediate analogue nag-thiazoline
Deposited on 2003-01-16, released 2003-04-29
The last revision prior to the SCOP 1.65 freeze date was dated 2003-04-29, with a file datestamp of 2003-04-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.2
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1np0A (A:)
akpgpalwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgfy
kwhhepaefqaktqvqqllvsitlqsecdafpnissdesytllvkepvavlkanrvwgal
rgletfsqlvyqdsygtftinestiidsprfshrgilidtsrhylpvkiilktldamafn
kfnvlhwhivddqsfpyqsitfpelsnkgsyslshvytpndvrmvieyarlrgirvlpef
dtpghtlswgkgqkdlltpcysrqnkldsfgpinptlnttysflttffkeisevfpdqfi
hlggdevefkcwesnpkiqdfmrqkgfgtdfkklesfyiqkvldiiatinkgsivwqevf
ddkaklapgtivevwkdsaypeelsrvtasgfpvilsapwyldlisygqdwrkyykvepl
dfggtqkqkqlfiggeaclwgeyvdatnltprlwprasavgerlwsskdvrdmddaydrl
trhrcrmvergiaaqplyagycnhenm

    Sequence, based on observed residues (ATOM records): (download) 
    >1np0A (A:)
alwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgtqvqqll
vsitlqsecdafpnissdesytllvkepvavlkanrvwgalrgletfsqlvyqdsygtft
inestiidsprfshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqs
itfpelsnkgsyslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltp
cysldsfgpinptlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmr
qkgfgtdfkklesfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypee
lsrvtasgfpvilsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgey
vdatnltprlwprasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1np0B (B:)
akpgpalwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgfy
kwhhepaefqaktqvqqllvsitlqsecdafpnissdesytllvkepvavlkanrvwgal
rgletfsqlvyqdsygtftinestiidsprfshrgilidtsrhylpvkiilktldamafn
kfnvlhwhivddqsfpyqsitfpelsnkgsyslshvytpndvrmvieyarlrgirvlpef
dtpghtlswgkgqkdlltpcysrqnkldsfgpinptlnttysflttffkeisevfpdqfi
hlggdevefkcwesnpkiqdfmrqkgfgtdfkklesfyiqkvldiiatinkgsivwqevf
ddkaklapgtivevwkdsaypeelsrvtasgfpvilsapwyldlisygqdwrkyykvepl
dfggtqkqkqlfiggeaclwgeyvdatnltprlwprasavgerlwsskdvrdmddaydrl
trhrcrmvergiaaqplyagycnhenm

    Sequence, based on observed residues (ATOM records): (download) 
    >1np0B (B:)
alwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgtqvqqll
vsitlqsecdafpnissdesytllvkepvavlkanrvwgalrgletfsqlvyqdsygtft
inestiidsprfshrgilidtsrhylpvkiilktldamafnkfnvlhwhivddqsfpyqs
itfpelsnkgsyslshvytpndvrmvieyarlrgirvlpefdtpghtlswgkgqkdlltp
cysldsfgpinptlnttysflttffkeisevfpdqfihlggdevefkcwesnpkiqdfmr
qkgfgtdfkklesfyiqkvldiiatinkgsivwqevfddkaklapgtivevwkdsaypee
lsrvtasgfpvilsapwyldlisygqdwrkyykvepldfggtqkqkqlfiggeaclwgey
vdatnltprlwprasavgerlwsskdvrdmddaydrltrhrcrmvergiaaqplyagycn