PDB entry 1nmz

View 1nmz on RCSB PDB site
Description: Crystal structure of human thymidylate kinase with NH2TMP and AppNHp
Class: transferase
Keywords: thymidylate kinase, p-loop, aminothymidine, TRANSFERASE
Deposited on 2003-01-12, released 2003-03-18
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.186
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: similar to THYMIDYLATE KINASE (DTMP KINASE)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23919 (Start-214)
      • engineered (202)
    Domains in SCOPe 2.05: d1nmza_
  • Heterogens: MG, NYM, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nmzA (A:)
gshmaarrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssyl
qkksdvedhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwc
kqpdvglpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkm
vdasksieavhedirvlsedaiatatekplgelwk

    Sequence, based on observed residues (ATOM records): (download) 
    >1nmzA (A:)
rrgalivlegvdragkstqsrklvealcaaghraellrfpersteigkllssylqkksdv
edhsvhllfsanrweqvplikeklsqgvtlvvdryafsgvaftgakenfsldwckqpdvg
lpkpdlvlflqlqladaakrgafgheryengafqeralrcfhqlmkdttlnwkmvdasks
ieavhedirvlsedaiatatekplgelwk