PDB entry 1nm6

View 1nm6 on RCSB PDB site
Description: thrombin in complex with selective macrocyclic inhibitor at 1.8A
Class: blood clotting/hydrolase inhibitor
Keywords: thrombin inhibitor complex, BLOOD CLOTTING-HYDROLASE INHIBITOR COMPLEX
Deposited on 2003-01-09, released 2003-09-02
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.216
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1nm6a_
  • Chain 'B':
    Compound: hirudin
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28504 (0-10)
      • conflict (10)
  • Heterogens: L86, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nm6A (A:)
dcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcgas
lisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpryn
wrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtan
vgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvm
kspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

    Sequence, based on observed residues (ATOM records): (download) 
    >1nm6A (A:)
dcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgaslis
drwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwre
nldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqpsvlqv
vnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqm
givswgegcdrdgkygfythvfrlkkwiqkvidqfg

  • Chain 'B':
    No sequence available.