PDB entry 1njt

View 1njt on RCSB PDB site
Description: complex structure of hcmv protease and a peptidomimetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: protease, peptidomimetic inhibitor, induced-fit, hydrolase-hydrolase inhibitor complex
Deposited on 2003-01-02, released 2003-02-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.228
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Capsid protein P40
    Species: Human herpesvirus 5 [TaxId:10359]
    Gene: UL80 OR APNG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1njta_
  • Chain 'B':
    Compound: Capsid protein P40
    Species: Human herpesvirus 5 [TaxId:10359]
    Gene: UL80 OR APNG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1njtb_
  • Chain 'C':
    Compound: Capsid protein P40
    Species: Human herpesvirus 5 [TaxId:10359]
    Gene: UL80 OR APNG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1njtc_
  • Chain 'D':
    Compound: Capsid protein P40
    Species: Human herpesvirus 5 [TaxId:10359]
    Gene: UL80 OR APNG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1njtd_
  • Chain 'E':
    Compound: peptidomimetic inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1NJT
  • Chain 'F':
    Compound: peptidomimetic inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1NJT
  • Chain 'G':
    Compound: peptidomimetic inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1NJT
  • Chain 'H':
    Compound: peptidomimetic inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1NJT (Start-4)
  • Heterogens: CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1njtA (A:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
tqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdalyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >1njtA (A:)
mdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqvalplninhddtavvg
hvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsyag
lslssrrcdtpfkhvalcsvgrrrgtlavygrdpewvtqrfpdltaadrdglraqwqrcg
gdpfrsdsygllgnsvdalyirerlpklrydkqlvgvteresyvka

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1njtB (B:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
tqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdalyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >1njtB (B:)
tmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqalplninhddtavvg
hvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsyag
lslssrrcdttpfkhvalcsvgrrrgtlavygrdpewvtqrfpdltaadrdglraqwqrc
sgdpfrsdsygllgnsvdalyirerlpklrydkqlvgvteresyvka

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1njtC (C:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
tqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdalyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >1njtC (C:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhaalplninhddtavvghva
amqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsyaglsl
ssrrcdttpfkhvalcsvgrrrgtlavygrdpewvtqrfpdltaadrdglraqwqsgdpf
rsdsygllgnsvdalyirerlpklrydkqlvgvteresyvka

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1njtD (D:)
mtmdeqqsqavapvyvggflarydqspdeaelllprdvvehwlhaqgqgqpslsvalpln
inhddtavvghvaamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkv
veflsgsyaglslssrrcddveqatslsgsettpfkhvalcsvgrrrgtlavygrdpewv
tqrfpdltaadrdglraqwqrcgstavdasgdpfrsdsygllgnsvdalyirerlpklry
dkqlvgvteresyvka

    Sequence, based on observed residues (ATOM records): (download) 
    >1njtD (D:)
deqqsqavapvyvggflarydqspdeaelllprdvvehwlhavalplninhddtavvghv
aamqsvrdglfclgcvtsprfleivrrasekselvsrgpvsplqpdkvveflsgsyagls
lssrrcttpfkhvalcsvgrrrgtlavygrdpewvtqrfpdltaadrdglraqwqasgdp
frsdsygllgnsvdalyirerlpklrydkqlvgvteresyvka

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.