PDB entry 1njd

View 1njd on RCSB PDB site
Description: thymidylate synthase, mutation, n229d with 2'-deoxyuridine 5'-monophosphate (dump)
Class: transferase (methyltransferase)
Keywords: transferase, methyltransferase, nucleotide biosynthesis, transferase (methyltransferase)
Deposited on 1996-01-23, released 1996-07-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.194
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Lactobacillus casei [TaxId:1582]
    Gene: N229D MUTANT OF CLONED L. CASE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00469 (0-315)
      • engineered (228)
    Domains in SCOPe 2.06: d1njda_
  • Heterogens: UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1njdA (A:)
    mleqpyldlakkvldeghfkpdrthtgtysifghqmrfdlskgfpllttkkvpfglikse
    llwflhgdtnirfllqhrnhiwdewafekwvksdeyhgpdmtdfghrsqkdpefaavyhe
    emakfddrvlhddafaakygdlglvygsqwrawhtskgdtidqlgdvieqikthpysrrl
    ivsawnpedvptmalppchtlyqfyvndgklslqlyqrsadiflgvpfdiasyallthlv
    ahecglevgefihtfgdahlyvnhldqikeqlsrtprpaptlqlnpdkhdifdfdmkdik
    llnydpypaikapvav