PDB entry 1ngv

View 1ngv on RCSB PDB site
Description: Insights into the ubiquitin transfer cascade from the structure of the E1 for NEDD8.
Class: signaling protein
Keywords: signaling protein
Deposited on 2002-12-17, released 2003-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2005-03-08, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.23
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: amyloid beta precursor protein-binding protein 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB NP_003896 (Start-533)
    Domains in SCOPe 2.08: d1ngva_
  • Chain 'B':
    Compound: uba3
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB AAC27648
    Domains in SCOPe 2.08: d1ngvb_
  • Chain 'C':
    Compound: amyloid beta precursor protein-binding protein 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB NP_003896 (Start-533)
    Domains in SCOPe 2.08: d1ngvc_
  • Chain 'D':
    Compound: uba3
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • GB AAC27648
    Domains in SCOPe 2.08: d1ngvd_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ngvA (A:)
maqlgkllkeqkydrqlrlwgdhgqealesahvclinatatgteilknlvlpgigsftii
dgnqvsgedagnnfflqrssigknraeaameflqelnsdvsgsfveespenlldndpsff
crftvvvatqlpestslrladvlwnsqipllicrtyglvgymriiikehpvieshpdnal
edlrldkpfpelrehfqsydldhmekkdhshtpwiviiakylaqwysetngripktykek
edfrdlirqgilknengapedeenfeeaiknvntalnttqipssiedifnddrcinitkq
tpsfwilaralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaavgnh
vakllqsigqapesisekelkllcsnsaflrvvrcrslaeeygldtinkdeiissmdnpd
neivlylmlravdrfhkqqgrypgvsnyqveedigklkscltgflqeyglsvmvkddyvh
efcrygaaephtiaaflggaaaqevikiitkqfvifnntyiysgmsqtsatfql

    Sequence, based on observed residues (ATOM records): (download) 
    >1ngvA (A:)
kllkeqkydrqlrlwgdhgqealesahvclinatatgteilknlvlpgigsftiidgnqv
sgedagnnfflqrssigknraeaameflqelnsdvsgsfveespenlldndpsffcrftv
vvatqlpestslrladvlwnsqipllicrtyglvgymriiikehpvieshpdnaledlrl
dkpfpelrehfqsydldhmekkdhshtpwiviiakylaqwysetngripktykekedfrd
lirqgilknengapedeenfeeaiknvntalnttqipssiedifnddrcinitkqtpsfw
ilaralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaavgnhvakll
qsigqapesisekelkllcsnsaflrvvrcrslaeeygldtinkdeiissmdnpdneivl
ylmlravdrfhkqqgrypgvsnyqveedigklkscltgflqeyglsvmvkddyvhefcry
gaaephtiaaflggaaaqevikiitkqfvifnntyiysgmsqtsatfql

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ngvB (B:)
mavdggcgdtgdwegrwnhvkkflersgpfthpdfepsteslqflldtckvlvigagglg
cellknlalsgfrqihvidmdtidvsnlnrqflfrpkdigrpkaevaaeflndrvpncnv
vphfnkiqdfndtfyrqfhiivcgldsiiarrwingmlisllnyedgvldpssivplidg
gtegfkgnarvilpgmtaciectlelyppqvnfpmctiasmprlpehcieyvrmlqwpke
qpfgegvpldgddpehiqwifqkslerasqynirgvtyrltqgvvkriipavastnavia
avcatevfkiatsayiplnnylvfndvdglytytfeaerkencpacsqlpqniqfspsak
lqevldyltnsaslqmkspaitatlegknrtlylqsvtsieertrpnlsktlkelglvdg
qelavadvttpqtvlfklhfts

    Sequence, based on observed residues (ATOM records): (download) 
    >1ngvB (B:)
dwegrwnhvkkflersgpfthpdfepsteslqflldtckvlvigagglgcellknlalsg
frqihvidmdtidvsnlnrqflfrpkdigrpkaevaaeflndrvpncnvvphfnkiqdfn
dtfyrqfhiivcgldsiiarrwingmlisllnyedgvldpssivplidggtegfkgnarv
ilpgmtaciectlelyppqvnfpmctiasmprlpehcieyvrmlqwpkeqpfgegvpldg
ddpehiqwifqkslerasqynirgvtyrltqgvvkriipavastnaviaavcatevfkia
tsayiplnnylvfndvdglytytfeaerkencpacsqlpqniqlqevldyltnsaslqmk
spaitatrtlylqseertrpnladvttpqtvlfklhft

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ngvC (C:)
maqlgkllkeqkydrqlrlwgdhgqealesahvclinatatgteilknlvlpgigsftii
dgnqvsgedagnnfflqrssigknraeaameflqelnsdvsgsfveespenlldndpsff
crftvvvatqlpestslrladvlwnsqipllicrtyglvgymriiikehpvieshpdnal
edlrldkpfpelrehfqsydldhmekkdhshtpwiviiakylaqwysetngripktykek
edfrdlirqgilknengapedeenfeeaiknvntalnttqipssiedifnddrcinitkq
tpsfwilaralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaavgnh
vakllqsigqapesisekelkllcsnsaflrvvrcrslaeeygldtinkdeiissmdnpd
neivlylmlravdrfhkqqgrypgvsnyqveedigklkscltgflqeyglsvmvkddyvh
efcrygaaephtiaaflggaaaqevikiitkqfvifnntyiysgmsqtsatfql

    Sequence, based on observed residues (ATOM records): (download) 
    >1ngvC (C:)
keqkydrqlrlwgdhgqealesahvclinatatgteilknlvlpgigsftiidgnqvsge
dagnnfflqrssigknraeaameflqelnsdvsgsfveespenlldndpsffcrftvvva
tqlpestslrladvlwnsqipllicrtyglvgymriiikehpvieshpdnaledlrldkp
fpelrehfqsydldhmekkdhshtpwiviiakylaqwysetngripktykekedfrdlir
qgilknengapedeenfeeaiknvntalnttqipssiedifnddrcinitkqtpsfwila
ralkefvakegqgnlpvrgtipdmiadsgkyiklqnvyrekakkdaaavgnhvakllqsi
gqapesisekelkllcsnsaflrvvrcrslaeeygldtinkdeiissmdnpdneivlylm
lravdrfhkqqgrypgvsnyqveedigklkscltgflqeyglsvmvkddyvhefcrygaa
ephtiaaflggaaaqevikiitkqfvifnntyiysgmsqtsatfql

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ngvD (D:)
mavdggcgdtgdwegrwnhvkkflersgpfthpdfepsteslqflldtckvlvigagglg
cellknlalsgfrqihvidmdtidvsnlnrqflfrpkdigrpkaevaaeflndrvpncnv
vphfnkiqdfndtfyrqfhiivcgldsiiarrwingmlisllnyedgvldpssivplidg
gtegfkgnarvilpgmtaciectlelyppqvnfpmctiasmprlpehcieyvrmlqwpke
qpfgegvpldgddpehiqwifqkslerasqynirgvtyrltqgvvkriipavastnavia
avcatevfkiatsayiplnnylvfndvdglytytfeaerkencpacsqlpqniqfspsak
lqevldyltnsaslqmkspaitatlegknrtlylqsvtsieertrpnlsktlkelglvdg
qelavadvttpqtvlfklhfts

    Sequence, based on observed residues (ATOM records): (download) 
    >1ngvD (D:)
hvkkflersgpfthpdfepsteslqflldtckvlvigagglgcellknlalsgfrqihvi
dmdtidvsnlnrqflfrpkdigrpkaevaaeflndrvpncnvvphfnkiqdfndtfyrqf
hiivcgldsiiarrwingmlisllnyedgvldpssivplidggtegfkgnarvilpgmta
ciectlelyppqvnfpmctiasmprlpehcieyvrmlqwpkeqpfgegvpldgddpehiq
wifqkslerasqynirgvtyrltqgvvkriipavastnaviaavcatevfkiatsayipl
nnylvfndvdglytytfeaerkencpacsqlpqniqlqevldyltnsaslqmkspaitnr
tlylqsveertradvttpqtvlfklhf