PDB entry 1nfb

View 1nfb on RCSB PDB site
Description: Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with 6Cl-IMP and NAD
Class: oxidoreductase
Keywords: 8 stranded paralle alpha/beta barrel, dehydrogenase, impd, impdh, guanine nucleotide biosynthesis nad
Deposited on 2002-12-13, released 2004-01-27
The last revision prior to the SCOP 1.75 freeze date was dated 2004-01-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.229
AEROSPACI score: -1.79 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: HOMO SAPIENS
    Gene: IMPDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1nfba1, d1nfba4
  • Chain 'B':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: HOMO SAPIENS
    Gene: IMPDH2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1nfbb1, d1nfbb4
  • Heterogens: CPR, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nfbA (A:)
madylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkit
lktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvv
lspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdcfleeimt
kredlvvapagitlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplaskda
kkqllcgaaigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqvi
ggnvvtaaqaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvp
viadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldam
dkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvr
ammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records): (download) 
    >1nfbA (A:)
tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp
mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvvlspgipitd
tgrmgsapagitlkeaneilqrskkgklpivneddevaiianrdyplaskdakkqllcga
aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa
qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq
nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmdkgsihkfvpylia
giqhscqdigaksltqvrammysgelkfekrtssaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1nfbB (B:)
madylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkit
lktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvv
lspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdcfleeimt
kredlvvapagitlkeaneilqrskkgklpivneddelvaiiartdlkknrdyplaskda
kkqllcgaaigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqvi
ggnvvtaaqaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvp
viadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldam
dkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvr
ammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records): (download) 
    >1nfbB (B:)
tsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvssp
mdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvvlspgipitd
tgrmgsapagitlkeaneilqrskkgklpivneddevaiianrdyplaskdakkqllcga
aigtheddkyrldllaqagvdvvvldssqgnsifqinmikyikdkypnlqviggnvvtaa
qaknlidagvdalrvgmgsgsicitqevlacgrpqatavykvseyarrfgvpviadggiq
nvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmdkgsihkfvpylia
giqhscqdigaksltqvrammysgelkfekrtssaq