PDB entry 1n5l

View 1n5l on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis thymidylate kinase crystallized in sodium malonate, after catalysis in the crystal (2.3 a resolution)
Class: transferase
Keywords: transferase (ATP:tmp phosphotransferase), kinase
Deposited on 2002-11-06, released 2003-04-15
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-15, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.236
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n5la_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n5lb_
  • Heterogens: MG, ACT, TMP, TYD, DPO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1n5lA (A:)
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatlappdvps

    Sequence, based on observed residues (ATOM records): (download) 
    >1n5lA (A:)
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagerdnyerdaelqqrtgavyaelaaqgwggrwlv
vgadvdpgrlaatla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1n5lB (B:)
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgraqrdpgrardnyerdaelqqrtgavya
elaaqgwggrwlvvgadvdpgrlaatlappdvps

    Sequence, based on observed residues (ATOM records): (download) 
    >1n5lB (B:)
mliaiegvdgagkrtlveklsgafraagrsvatlafprygqsvaadiaaealhgehgdla
ssvyamatlfaldragavhtiqglcrgydvvildryvasnaaysaarlhenaagkaaawv
qriefarlglpkpdwqvllavsaelagersrgrarardnyerdaelqqrtgavyaelaaq
gwggrwlvvgadvdpgrlaatla