PDB entry 1n4r

View 1n4r on RCSB PDB site
Description: Protein Geranylgeranyltransferase type-I Complexed with a Geranylgeranylated KKKSKTKCVIL Peptide Product
Class: transferase
Keywords: protein geranylgeranyltransferase type-I, GGTase, geranylgeranyl, protein prenylation, CaaX, lipid modification, rap2b
Deposited on 2002-11-01, released 2003-11-18
The last revision prior to the SCOP 1.75 freeze date was dated 2003-11-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4ra_
  • Chain 'B':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rb_
  • Chain 'C':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rc_
  • Chain 'D':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rd_
  • Chain 'E':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4re_
  • Chain 'F':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rf_
  • Chain 'G':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rg_
  • Chain 'H':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rh_
  • Chain 'I':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4ri_
  • Chain 'J':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rj_
  • Chain 'K':
    Compound: protein farnesyltransferase alpha subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rk_
  • Chain 'L':
    Compound: geranyltransferase type-I beta subunit
    Species: Rattus norvegicus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1n4rl_
  • Chain 'M':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, CL, SO4, MES, TTH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1n4rA (A:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rA (A:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1n4rB (B:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rB (B:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1n4rC (C:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rC (C:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1n4rD (D:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rD (D:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1n4rE (E:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rE (E:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1n4rF (F:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rF (F:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1n4rG (G:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rG (G:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1n4rH (H:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rH (H:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1n4rI (I:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rI (I:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1n4rJ (J:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rJ (J:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1n4rK (K:)
maategvgesapggepgqpeqpppppppppaqqpqeeemaaeageaaaspmddgflslds
ptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderserafklt
rdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrvlvewlk
dpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnnsvwnqr
hfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypnllnqll
dlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirkeywryig
rslqskhsresdipasv

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rK (K:)
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhs

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1n4rL (L:)
maateddrlagsgegerldflrdrhvrffqrclqvlperyssletsrltiaffalsgldm
ldsldvvnkddiiewiyslqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsg
hiamtytglscliilgddlsrvdkeaclaglralqledgsfcavpegsendmrfvycasc
icymlnnwsgmdmkkaisyirrsmsydnglaqgagleshggstfcgiaslclmgkleevf
sekelnrikrwcimrqqngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyils
tqdrlvggfakwpdshpdalhayfgicglslmeesgickvhpalnvstrtserlrdlhqs
wktkdskqcsdnvhiss

    Sequence, based on observed residues (ATOM records): (download) 
    >1n4rL (L:)
ldflrdrhvrffqrclqvlperyssletsrltiaffalsgldmldsldvvnkddiiewiy
slqvlptedrsnldrcgfrgssylgipfnpsknpgtahpydsghiamtytglscliilgd
dlsrvdkeaclaglralqledgsfcavpegsendmrfvycascicymlnnwsgmdmkkai
syirrsmsydnglaqgagleshggstfcgiaslclmgkleevfsekelnrikrwcimrqq
ngyhgrpnkpvdtcysfwvgatlkllkifqytnfeknrnyilstqdrlvggfakwpdshp
dalhayfgicglslmeesgickvhpalnvstrtserlrdlhqswkt

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.