PDB entry 1n3t

View 1n3t on RCSB PDB site
Description: Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
Class: hydrolase
Keywords: Biosynthesis, folic acid, crystal structure, GTP cyclohydrolase I, tetrahydropterin, pteridines
Deposited on 2002-10-29, released 2003-10-14
The last revision prior to the SCOP 1.73 freeze date was dated 2003-10-14, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.185
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3ta_
  • Chain 'B':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tb_
  • Chain 'C':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tc_
  • Chain 'D':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3td_
  • Chain 'E':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3te_
  • Chain 'F':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tf_
  • Chain 'G':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tg_
  • Chain 'H':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3th_
  • Chain 'I':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3ti_
  • Chain 'J':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tj_
  • Chain 'K':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tk_
  • Chain 'L':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tl_
  • Chain 'M':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tm_
  • Chain 'N':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3tn_
  • Chain 'O':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (180)
    Domains in SCOP 1.73: d1n3to_
  • Heterogens: GTP

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tA (A:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tB (B:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tC (C:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tD (D:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tE (E:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tF (F:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tG (G:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tH (H:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tI (I:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tJ (J:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tK (K:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tL (L:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tM (M:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tN (N:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3tO (O:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
svkargirdatsattttslgglfkssqntrheflravrhhn