PDB entry 1n3s

View 1n3s on RCSB PDB site
Description: Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
Class: hydrolase
Keywords: Biosynthesis, folic acid, crystal structure, GTP cyclohydrolase I, tetrahydropterin, pteridines
Deposited on 2002-10-29, released 2004-03-02
The last revision prior to the SCOP 1.73 freeze date was dated 2004-03-02, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.262
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sa_
  • Chain 'B':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sb_
  • Chain 'C':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sc_
  • Chain 'D':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sd_
  • Chain 'E':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3se_
  • Chain 'F':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sf_
  • Chain 'G':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sg_
  • Chain 'H':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sh_
  • Chain 'I':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3si_
  • Chain 'J':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (112)
    Domains in SCOP 1.73: d1n3sj_
  • Heterogens: GTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sA (A:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sB (B:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sC (C:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sD (D:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sE (E:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sF (F:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sG (G:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sH (H:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sI (I:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3sJ (J:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehsfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn