PDB entry 1n3r

View 1n3r on RCSB PDB site
Description: Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
Class: hydrolase
Keywords: Biosynthesis, folic acid, crystal structure, GTP cyclohydrolase I, tetrahydropterin, pteridines
Deposited on 2002-10-29, released 2003-10-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.218
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3ra_
  • Chain 'B':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rb_
  • Chain 'C':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rc_
  • Chain 'D':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rd_
  • Chain 'E':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-End)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3re_
  • Chain 'F':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rf_
  • Chain 'G':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rg_
  • Chain 'H':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rh_
  • Chain 'I':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3ri_
  • Chain 'J':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rj_
  • Chain 'K':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rk_
  • Chain 'L':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rl_
  • Chain 'M':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rm_
  • Chain 'N':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3rn_
  • Chain 'O':
    Compound: GTP cyclohydrolase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A6T5 (0-220)
      • engineered (111)
    Domains in SCOPe 2.06: d1n3ro_
  • Heterogens: GTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rA (A:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rB (B:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rC (C:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rD (D:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1n3rE (E:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

    Sequence, based on observed residues (ATOM records): (download) 
    >1n3rE (E:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhh

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rF (F:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rG (G:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rH (H:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rI (I:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rJ (J:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rK (K:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rL (L:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rM (M:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rN (N:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n3rO (O:)
pslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslm
etphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstceshfvtidgk
atvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhy
cvkargirdatsattttslgglfkssqntrheflravrhhn