PDB entry 1n2r

View 1n2r on RCSB PDB site
Description: A natural selected dimorphism in HLA B*44 alters self, peptide reportoire and T cell recognition.
Class: immune system
Keywords: MHC I, signal, immune system
Deposited on 2002-10-24, released 2004-03-16
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.229
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, BW-44(B-12) B*4403 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-B or HLAB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1n2ra1, d1n2ra2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1n2rb_
  • Chain 'C':
    Compound: HLA DPA*0201 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • GB AAH09956 (0-8)
  • Heterogens: ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n2rA (A:)
gshsmryfytamsrpgrgeprfitvgyvddtlfvrfdsdatsprkeprapwieqegpeyw
dretqisktntqtyrenlrtalryynqseagshiiqrmygcdvgpdgrllrgydqdaydg
kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcveslrrylengketlq
radppkthvthhpisdhevtlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
fqkwaavvvpsgeeqrytchvqheglpkpltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1n2rB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.