PDB entry 1n2r
View 1n2r on RCSB PDB site
Description: A natural selected dimorphism in HLA B*44 alters self, peptide reportoire and T cell recognition.
Class: immune system
Keywords: MHC I, signal, immune system
Deposited on
2002-10-24, released
2004-03-16
The last revision prior to the SCOP 1.75 freeze date was dated
2004-03-16, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.229
AEROSPACI score: 0.63
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: HLA class I histocompatibility antigen, BW-44(B-12) B*4403 alpha chain
Species: HOMO SAPIENS
Gene: HLA-B or HLAB
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1n2ra1, d1n2ra2 - Chain 'B':
Compound: Beta-2-microglobulin
Species: HOMO SAPIENS
Gene: B2M
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1n2rb_ - Chain 'C':
Compound: HLA DPA*0201 peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: ACY, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1n2rA (A:)
gshsmryfytamsrpgrgeprfitvgyvddtlfvrfdsdatsprkeprapwieqegpeyw
dretqisktntqtyrenlrtalryynqseagshiiqrmygcdvgpdgrllrgydqdaydg
kdyialnedlsswtaadtaaqitqrkweaarvaeqlrayleglcveslrrylengketlq
radppkthvthhpisdhevtlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdrt
fqkwaavvvpsgeeqrytchvqheglpkpltlrwep
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1n2rB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.