PDB entry 1n0w

View 1n0w on RCSB PDB site
Description: Crystal structure of a RAD51-BRCA2 BRC repeat complex
Class: gene regulation/antitumor protein
Keywords: DNA repair, homologous recombination, breast cancer susceptibility, RecA-like ATPase, protein complex, GENE REGULATION/ANTITUMOR PROTEIN COMPLEX
Deposited on 2002-10-15, released 2002-11-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.191
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA repair protein RAD51 homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAD51
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06609 (Start-242)
      • modified residue (28)
      • modified residue (61)
      • modified residue (113-114)
      • modified residue (146)
      • modified residue (154)
      • modified residue (229)
    Domains in SCOPe 2.06: d1n0wa_
  • Chain 'B':
    Compound: Breast Cancer type 2 susceptibility protein
    Species: Homo sapiens [TaxId:9606]
    Gene: BRCA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1n0wb_
  • Chain 'C':
    Compound: artificial gly-ser-mse-gly peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1N0W (0-3)
  • Chain 'L':
    Compound: Peptide linker
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1N0W
  • Heterogens: MG, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1n0wA (A:)
seiiqittgskeldkllqggietgsitemfgefrtgktqichtlavtcqlpidrgggegk
amyidtegtfrperllavaeryglsgsdvldnvayarafntdhqtqllyqasammvesry
allivdsatalyrtdysgrgelsarqmhlarflrmllrladefgvavvitnqvvaqvdga
amfaadpkkpiggniiahasttrlylrkgrgetrickiydspclpeaeamfainadgvgd
akd

    Sequence, based on observed residues (ATOM records): (download) 
    >1n0wA (A:)
eiiqittgskeldkllqggietgsitemfgefrtgktqichtlavtcqlpidrgggegka
myidtegtfrperllavaeryglsgsdvldnvayarafntdhqtqllyqasammvesrya
llivdsatalyrelsarqmhlarflrmllrladefgvavvitnahasttrlylrkgrget
rickiydspclpeaeamfainadgvgdakd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1n0wB (B:)
keptllgfhtasgkkvkiakesldkvknlfdekeq

    Sequence, based on observed residues (ATOM records): (download) 
    >1n0wB (B:)
ptllgfhtasgkkvkiakesldkvknlfdekeq

  • Chain 'C':
    No sequence available.

  • Chain 'L':
    No sequence available.