PDB entry 1mzn

View 1mzn on RCSB PDB site
Description: CRYSTAL STRUCTURE at 1.9 ANGSTROEMS RESOLUTION OF THE HOMODIMER OF HUMAN RXR ALPHA LIGAND BINDING DOMAIN BOUND TO THE SYNTHETIC AGONIST COMPOUND BMS 649 AND A COACTIVATOR PEPTIDE
Class: Transcription
Keywords: Transcription, Nuclear Receptor, Retinoic Acid Receptors, Agonist
Deposited on 2002-10-09, released 2002-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.195
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RXR retinoid X receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mzna_
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: RXR retinoid X receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mznc_
  • Chain 'D':
    Compound: nuclear receptor coactivator 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: RXR retinoid X receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mzne_
  • Chain 'F':
    Compound: nuclear receptor coactivator 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: RXR retinoid X receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mzng_
  • Chain 'H':
    Compound: nuclear receptor coactivator 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BM6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mznA (A:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >1mznA (A:)
nedmpverileaelavepktetyveanndpvtnicqaadkqlftlvewakriphfselpl
ddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelv
skmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgr
faklllrlpalrsiglkclehlfffkligdtpidtflmemleap

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1mznC (C:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >1mznC (C:)
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdtpidtflmemleap

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1mznE (E:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >1mznE (E:)
nedmpverileaelavepktetyveanndpvtnicqaadkqlftlvewakriphfselpl
ddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelv
skmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgr
faklllrlpalrsiglkclehlfffkligdtpidtflmemleap

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1mznG (G:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt

    Sequence, based on observed residues (ATOM records): (download) 
    >1mznG (G:)
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdtpidtflmemleap

  • Chain 'H':
    No sequence available.