PDB entry 1mx5

View 1mx5 on RCSB PDB site
Description: crystal structure of human liver carboxylesterase in complexed with homatropine, a cocaine analogue
Deposited on 2002-10-01, released 2003-04-08
The last revision prior to the SCOP 1.69 freeze date was dated 2003-04-29, with a file datestamp of 2003-04-29.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.158
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Domains in SCOP 1.69: d1mx5a_
  • Chain 'B':
    Domains in SCOP 1.69: d1mx5b_
  • Chain 'C':
    Domains in SCOP 1.69: d1mx5c_
  • Chain 'D':
    Domains in SCOP 1.69: d1mx5d_
  • Chain 'E':
    Domains in SCOP 1.69: d1mx5e_
  • Chain 'F':
    Domains in SCOP 1.69: d1mx5f_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mx5A (A:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5A (A:)
ssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvkna
tsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwih
ggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrw
vqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgd
vkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllg
tvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsl
lwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdag
aptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwa
nfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1mx5B (B:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5B (B:)
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1mx5C (C:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5C (C:)
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1mx5D (D:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5D (D:)
ssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvkna
tsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwih
ggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrw
vqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgd
vkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllg
tvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsl
lwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdag
aptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwa
nfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1mx5E (E:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5E (E:)
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1mx5F (F:)
hpssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvk
natsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvw
ihggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaal
rwvqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkk
gdvkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpl
lgtvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktam
sllwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrd
agaptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkf
wanfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfakkavekp
pqtehiel

    Sequence, based on observed residues (ATOM records): (download) 
    >1mx5F (F:)
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak