PDB entry 1mvc
View 1mvc on RCSB PDB site
Description: Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide
Class: Transcription
Keywords: Nuclear Receptor, Retinoic Acid, Agonist recognition, Transcription Factor
Deposited on
2002-09-24, released
2002-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.201
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: RXR retinoid X receptor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1mvca_ - Chain 'B':
Compound: nuclear receptor coactivator 2
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: BM6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1mvcA (A:)
tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
Sequence, based on observed residues (ATOM records): (download)
>1mvcA (A:)
dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
siglkclehlfffkligdtpidtflmemleap
- Chain 'B':
No sequence available.