PDB entry 1mvc

View 1mvc on RCSB PDB site
Description: Crystal structure of the human RXR alpha ligand binding domain bound to the synthetic agonist compound BMS 649 and a coactivator peptide
Class: Transcription
Keywords: Nuclear Receptor, Retinoic Acid, Agonist recognition, Transcription Factor
Deposited on 2002-09-24, released 2002-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.201
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RXR retinoid X receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mvca_
  • Chain 'B':
    Compound: nuclear receptor coactivator 2
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BM6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1mvcA (A:)
    tssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvew
    akriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagv
    gaifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyaslea
    yckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mvcA (A:)
    dmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvillragwn
    elliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmdkte
    lgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlpalr
    siglkclehlfffkligdtpidtflmemleap
    

  • Chain 'B':
    No sequence available.