PDB entry 1mu6
View 1mu6 on RCSB PDB site
Description: Crystal Structure of Thrombin in Complex with L-378,622
Class: hydrolase/blood clotting
Keywords: hydrolase, blood clotting
Deposited on
2002-09-23, released
2004-04-06
The last revision prior to the SCOP 1.75 freeze date was dated
2004-04-13, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: 0.206
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: thrombin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1mu6.1 - Chain 'B':
Compound: thrombin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1mu6.1 - Chain 'C':
Compound: hirudin iib
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: CDA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1mu6A (A:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1mu6A (A:)
dcglrplfekksledkterellesyi
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1mu6B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1mu6B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
wiqkvidqfg
- Chain 'C':
No sequence available.