PDB entry 1mu2

View 1mu2 on RCSB PDB site
Description: crystal structure of hiv-2 reverse transcriptase
Class: transferase
Keywords: hiv-2 reverse transcriptase, aids, polymerase, drug design
Deposited on 2002-09-23, released 2002-10-30
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.192
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-2 rt
    Species: Human immunodeficiency virus 2
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04584 (Start-554)
      • engineered (283)
      • see remark 999 (333)
      • see remark 999 (504)
    Domains in SCOP 1.73: d1mu2a1, d1mu2a2
  • Chain 'B':
    Compound: hiv-2 rt
    Species: Human immunodeficiency virus 2
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04584 (0-425)
      • engineered (278)
      • see remark 999 (328)
    Domains in SCOP 1.73: d1mu2b_
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mu2A (A:)
pvakvepikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntpt
faikkkdknkwrmlidfrelnkvtqdfteiqlgiphpaglakkrritvldvgdayfsipl
hedfrpytaftlpsvnnaepgkryiykvlpqgwkgspaifqhtmrqvlepfrkankdvii
iqymddiliasdrtdlehdrvvlqlkellnglgfstpdekfqkdppyhwmgyelwptkwk
lqkiqlpqkeiwtvndiqklvgvlnwaaqlypgiktkhlcrlisgkmtlteevqwtelae
aeleenriilsqeqeghyyqeekeleatvqkdqdnqwtykihqeekilkvgkyakvknth
tngirllaqvvqkigkealviwgripkfhlpvereiweqwwdnywqvtwipdwdfvstpp
lvrlafnlvgdpipgaetfytdgscnrqskegkagyvtdrgkdkvkkleqttnqqaelea
famaltdsgpkvniivdsqyvmgivasqpteseskivnqiieemikkeaiyvawvpahkg
iggnqevdhlvsqgi

    Sequence, based on observed residues (ATOM records): (download) 
    >1mu2A (A:)
akvepikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntptfa
ikkkdrmlidfrelnkvtqdfteiqlgiphpaglakkrritvldvgdayfsiplhedfrp
ytaftlkryiykvlpqgwkgspaifqhtmrqvlepfrkankdviiiqymddiliasdrtd
lehdrvvlqlkellnglgfstpdekfqkdppyhwmgyelwptkwklqkiqlpqkeiwtvn
diqklvgvlnwaaqlypgiktkhlcrlisgkmtlteevqwtelaeaeleenriilsqeqe
ghyyqeekeleatvqkdqdnqwtykihqeekilkvgkyakvthtngirllaqvvqkigke
alviwgripkfhlpvereiweqwwdnywqvtwipdwdfvstpplvrlafnlvgdpipgae
tfytdgscnrqskegkagyvtdrgkdkvkkleqttnqqaeleafamaltdsgpkvniivd
sqyvmgivasqpteseskivnqiieemikkeaiyvawvpahkgiggnqevdhlvsqgi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1mu2B (B:)
epikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntptfaikk
kdknkwrmlidfrelnkvtqdfteiqlgiphpaglakkrritvldvgdayfsiplhedfr
pytaftlpsvnnaepgkryiykvlpqgwkgspaifqhtmrqvlepfrkankdviiiqymd
diliasdrtdlehdrvvlqlkellnglgfstpdekfqkdppyhwmgyelwptkwklqkiq
lpqkeiwtvndiqklvgvlnwaaqlypgiktkhlcrlisgkmtlteevqwtelaeaelee
nriilsqeqeghyyqeekeleatvqkdqdnqwtykihqeekilkvgkyakvknthtngir
llaqvvqkigkealviwgripkfhlpvereiweqwwdnywqvtwipdwdfvstpplvrla
fnlvgd

    Sequence, based on observed residues (ATOM records): (download) 
    >1mu2B (B:)
epikimlkpgkdgpklrqwpltkekiealkeicekmekegqleeapptnpyntptfaikn
kwrmlidfrelnkvtqdfteiqphpaglakkrritvldvgdayfsiplhedfrpytaftl
psvnnaepgkryiykvlpqgwkgspaifqhtmrqvlepfrkankdviiiqymddiliasd
rtdlehdrvvlqlkellngwmgyelwptkwklqkiqlpqkeiwtvndiqklvgvlnwaaq
lypgiktkhlcrlisgkmtlteevqwtelaeaeleenriilsqeqeghyyqeekeleatv
qkdqdnqwtykihqeekilkvgkyakvknthtngirllaqvvqkigkealviwgripkfh
lpvereiweqwwdnywqvtwipdwdfvstpplvrlafnlvgd