PDB entry 1mtr

View 1mtr on RCSB PDB site
Description: hiv-1 protease complexed with a cyclic phe-ile-val peptidomimetic inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: ASPARTYL PROTEINASE, AIDS, ASPARTYL PROTEASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 1996-02-15, released 1996-08-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-09-19, with a file datestamp of 2012-09-14.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.179
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03369 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.07: d1mtra_
  • Chain 'B':
    Compound: hiv-1 protease
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03369 (0-98)
      • engineered (6)
      • engineered (32)
      • engineered (66)
      • engineered (94)
    Domains in SCOPe 2.07: d1mtrb_
  • Heterogens: SO4, PI6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1mtrA (A:)
    pqitlwkrplvtiriggqlkealldtgaddtvieemnlpgkwkpkmiggiggfikvrqyd
    qipveiaghkaigtvlvgptpvniigrnlltqigatlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1mtrB (B:)
    pqitlwkrplvtiriggqlkealldtgaddtvieemnlpgkwkpkmiggiggfikvrqyd
    qipveiaghkaigtvlvgptpvniigrnlltqigatlnf