PDB entry 1msv

View 1msv on RCSB PDB site
Description: The S68A S-adenosylmethionine decarboxylase proenzyme processing mutant.
Class: lyase
Keywords: spermidine biosynthesis, lyase, decarboxylase, pyruvate, s-adenosylmethionine, sandwich, allosteric enzyme, pyruvoyl
Deposited on 2002-09-19, released 2003-03-11
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.21
AEROSPACI score: -1.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: s-adenosylmethionine decarboxylase proenzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17707
      • engineered (67)
    Domains in SCOPe 2.01: d1msva_
  • Chain 'B':
    Compound: s-adenosylmethionine decarboxylase proenzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17707
      • engineered (67)
    Domains in SCOPe 2.01: d1msvb_
  • Heterogens: PUT, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1msvA (A:)
meaahffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkq
eayvlseasmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkp
shqgyphrnfqeeieflnaifpngaaycmgrmnsdcwylytldfpesrvisqpdqtleil
mseldpavmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtyw
tihitpepefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspq
kiegfkrldcqsamfndynfvftsfakkqqqqqshicrsqmvtsqqtssvvrqt

    Sequence, based on observed residues (ATOM records): (download) 
    >1msvA (A:)
ahffegtekllevwfsrqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvlseas
mfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyphrn
fqeeieflnaifpngaaycmgrmnsdcwylytldfpesrvisqpdqtleilmseldpavm
dqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpepe
fsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqkiegfkrld
cqsamfndynfvftsfakk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1msvB (B:)
meaahffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkq
eayvlseasmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkp
shqgyphrnfqeeieflnaifpngaaycmgrmnsdcwylytldfpesrvisqpdqtleil
mseldpavmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtyw
tihitpepefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspq
kiegfkrldcqsamfndynfvftsfakkqqqqqshicrsqmvtsqqtssvvrqt

    Sequence, based on observed residues (ATOM records): (download) 
    >1msvB (B:)
ahffegtekllevwfsrqqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvlsea
smfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyphr
nfqeeieflnaifpngaaycmgrmnsdcwylytldfpesrvisqpdqtleilmseldpav
mdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpep
efsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqkiegfkrl
dcqsamfndynfvftsfakk