PDB entry 1ms9

View 1ms9 on RCSB PDB site
Description: Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose
Class: hydrolase
Keywords: sialidase, trans-glycosylation, protein-acrbohydrate interactions, beta-propeller, Hydrolase
Deposited on 2002-09-19, released 2003-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Trans-sialidase
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q26964
      • engineered (71)
      • see remark 999 (275)
      • see remark 999 (489)
      • see remark 999 (497)
      • engineered (508-509)
      • engineered (533)
      • see remark 999 (571)
      • engineered (606)
      • engineered (610)
      • engineered (612)
    Domains in SCOPe 2.08: d1ms9a1, d1ms9a2
  • Chain 'B':
    Compound: Trans-sialidase
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q26964
      • engineered (71)
      • see remark 999 (275)
      • see remark 999 (489)
      • see remark 999 (497)
      • engineered (508-509)
      • engineered (533)
      • see remark 999 (571)
      • engineered (606)
      • engineered (610)
      • engineered (612)
    Domains in SCOPe 2.08: d1ms9b1, d1ms9b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ms9A (A:)
    mggshhhhhhgmaslapgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvm
    vaiadaryetsfdnslidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnkl
    yvlvgsynssrsywtshgdardwdillavgevtkstaggkitasikwgspvslkeffpae
    megmhtnqflggagvaivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsaf
    gcsepvalewegkliintrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsq
    ssftavtiegmrvmlfthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvl
    ykddklyclheinsnevyslvfarlvgelriiksvlqswknwdshlssictpadpaasss
    ergcgpavttvglvgflshsatktewedayrcvnastanaervpnglkfagvgggalwpv
    sqqgqnqryhfanhaftlvasvtihevpkgaspllgasldssggkkllglsydkrhqwqp
    iygstpvtptgswemgkryhvvltmankigsvyidgeplegsgqtvvpdertpdishfyv
    ggykrsgmptdsrvtvnnvllynrqlnaeeirtlflsqdligteahmd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ms9A (A:)
    apgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvmvaiadaryetsfdns
    lidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnklyvlvgsynssrsywt
    shgdardwdillavgevtkstaggkitasikwgspvslkeffpaemegmhtnqflggagv
    aivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsafgcsepvalewegkli
    intrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsqssftavtiegmrvml
    fthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvlykddklyclheinsn
    evyslvfarlvgelriiksvlqswknwdshlssictpagcgpavttvglvgflshsatkt
    ewedayrcvnastanaervpnglkfagvgggalwpvsqqgqnqryhfanhaftlvasvti
    hevpkgaspllgasldssggkkllglsydkrhqwqpiygstpvtptgswemgkryhvvlt
    mankigsvyidgeplegsgqtvvpdertpdishfyvggykrsgmptdsrvtvnnvllynr
    qlnaeeirtlflsqdligteah
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1ms9B (B:)
    mggshhhhhhgmaslapgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvm
    vaiadaryetsfdnslidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnkl
    yvlvgsynssrsywtshgdardwdillavgevtkstaggkitasikwgspvslkeffpae
    megmhtnqflggagvaivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsaf
    gcsepvalewegkliintrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsq
    ssftavtiegmrvmlfthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvl
    ykddklyclheinsnevyslvfarlvgelriiksvlqswknwdshlssictpadpaasss
    ergcgpavttvglvgflshsatktewedayrcvnastanaervpnglkfagvgggalwpv
    sqqgqnqryhfanhaftlvasvtihevpkgaspllgasldssggkkllglsydkrhqwqp
    iygstpvtptgswemgkryhvvltmankigsvyidgeplegsgqtvvpdertpdishfyv
    ggykrsgmptdsrvtvnnvllynrqlnaeeirtlflsqdligteahmd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ms9B (B:)
    apgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvmvaiadaryetsfdns
    lidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnklyvlvgsynssrsywt
    shgdardwdillavgevtkstaggkitasikwgspvslkeffpaemegmhtnqflggagv
    aivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsafgcsepvalewegkli
    intrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsqssftavtiegmrvml
    fthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvlykddklyclheinsn
    evyslvfarlvgelriiksvlqswknwdshlssictpagcgpavttvglvgflshsatkt
    ewedayrcvnastanaervpnglkfagvgggalwpvsqqgqnqryhfanhaftlvasvti
    hevpkgaspllgasldssggkkllglsydkrhqwqpiygstpvtptgswemgkryhvvlt
    mankigsvyidgeplegsgqtvvpdertpdishfyvggykrsgmptdsrvtvnnvllynr
    qlnaeeirtlflsqdligteahm