PDB entry 1mrq

View 1mrq on RCSB PDB site
Description: Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone
Class: oxidoreductase
Keywords: 20alpha-HSD, hydroxysteroid dehydrogenase, progesterone, ternary complex, OXIDOREDUCTASE
Deposited on 2002-09-18, released 2003-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member C1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q04828 (1-322)
      • cloning artifact (0)
    Domains in SCOPe 2.08: d1mrqa1, d1mrqa2
  • Heterogens: NAP, STR, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1mrqA (A:)
qdskyqcvklndghfmpvlgfgtyapaevpkskaleatklaieagfrhidsahlynneeq
vglairskiadgsvkredifytsklwcnshrpelvrpalerslknlqldyvdlylihfpv
svkpgeevipkdengkilfdtvdlcatweavekckdaglaksigvsnfnrrqlemilnkp
glkykpvcnqvechpyfnqrklldfckskdivlvaysalgshreepwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltseemkaidgln
rnvryltldifagppnypfsdey