PDB entry 1mik

View 1mik on RCSB PDB site
Description: the role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin a
Class: complex (isomerase/immunosuppressant)
Keywords: complex (isomerase/immunosuppressant)
Deposited on 1995-09-20, released 1996-03-08
The last revision prior to the SCOP 1.73 freeze date was dated 1996-03-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: 0.175
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: cyclophilin a
  Species: HOMO SAPIENS
  Gene: CYCLOPHILIN
  Database cross-references and differences (RAF-indexed):
  • Uniprot P05092 (1-164)
  Domains in SCOP 1.73: d1mika_
• Chain 'B':
  Compound: [(5-hydroxy)norvaline2]-cyclosporin
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1mikA (A:)
  mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
  mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
  wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgqle
  

  
  
• Chain 'B':
  No sequence available.