PDB entry 1mhw

View 1mhw on RCSB PDB site
Description: design of non-covalent inhibitors of human cathepsin l. from the 96- residue proregion to optimized tripeptides
Deposited on 2002-08-21, released 2002-12-11
The last revision prior to the SCOP 1.71 freeze date was dated 2003-02-11, with a file datestamp of 2003-02-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.185
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Domains in SCOP 1.71: d1mhw.1
  • Chain 'B':
    Domains in SCOP 1.71: d1mhw.2
  • Chain 'C':
    Domains in SCOP 1.71: d1mhw.1
  • Chain 'D':
    Domains in SCOP 1.71: d1mhw.2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1mhwA (A:)
    aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
    gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
    almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfest
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mhwA (A:)
    aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
    gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
    almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfes
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1mhwB (B:)
    aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
    gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
    almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfest
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mhwB (B:)
    aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
    gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
    almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfes
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1mhwC (C:)
    nnkywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mhwC (C:)
    nkywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1mhwD (D:)
    nnkywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mhwD (D:)
    nkywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv