PDB entry 1mh0

View 1mh0 on RCSB PDB site
Description: Crystal structure of the anticoagulant slow form of thrombin
Class: blood clotting
Keywords: thrombin, allostery, sodium binding, serine protease
Deposited on 2002-08-18, released 2002-11-08
The last revision prior to the SCOP 1.73 freeze date was dated 2002-11-08, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.219
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (2-286)
      • engineered (101)
    Domains in SCOP 1.73: d1mh0a_
  • Chain 'B':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (2-286)
      • engineered (101)
    Domains in SCOP 1.73: d1mh0b_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mh0A (A:)
adcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1mh0A (A:)
adcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsvl
qvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwy
qmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1mh0B (B:)
adcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1mh0B (B:)
adcglrplfekksledkterellesyiivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryeaniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsvl
qvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwy
qmgivswgegcdrdgkygfythvfrlkkwiqkvidqf