PDB entry 1mei

View 1mei on RCSB PDB site
Description: Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and mycophenolic acid bound
Class: oxidoreductase
Keywords: alpha beta barrel, OXIDOREDUCTASE
Deposited on 2002-08-08, released 2003-08-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.227
AEROSPACI score: -1.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inosine-5'-monophosphate dehydrogenase
    Species: Tritrichomonas foetus [TaxId:5724]
    Gene: IMPDH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1meia1
  • Heterogens: K, XMP, MOA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1meiA (A:)
    makyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimq
    svsgekmaialareggisfifgsqsiesqaamvhavknfkagfvvsdsnvkpdqtfadvl
    aisqrtthntvavtddgtphgvllglvtqrdypidltqtetkvsdmmtpfsklvtahqdt
    klseankiiwekklnalpiidddqhlryivfrkdydrsqvchnelvdsqkrylvgagint
    rdfrervpalveagadvlcidssdgfsewqkitigwirekygdkvkvgagnivdgegfry
    ladagadfikigigggsicitreqkgigrgqatavidvvaernkyfeetgiyipvcsdgg
    ivydyhmtlalamgadfimlgryfarfeesptrkvtingsvmkeywgegssrarnwqryd
    lggkqklsfeegvdsyvpyagklkdnveaslnkvkstmcncgaltipqlqskakitlvss
    vsiveggahdvivkdrindyhpk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1meiA (A:)
    akyynepchtfneyllipglstvdcipsnvnlstplvkfqkgqqseinlkiplvsaimqs
    vsgekmaialareggisfifgsqsiesqaamvhavknfkahnelvdsqkrylvgagintr
    dfrervpalveagadvlcidssdgfsewqkitigwirekygdkvkvgagnivdgegfryl
    adagadfikigigggsicitreqkgigrgqatavidvvaernkyfeetgiyipvcsdggi
    vydyhmtlalamgadfimlgryfarfeesptrkvtingsvmkeywgegssrarnwsfeeg
    vdsyvpyagklkdnveaslnkvkstmcncgaltipqlqskakitlvssvsi