PDB entry 1mdu

View 1mdu on RCSB PDB site
Description: Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1)
Class: Structural Protein
Keywords: gelsolin precursor, a-actin, ADENOSINE-5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1, 3-DIOL, Structural Protein
Deposited on 2002-08-07, released 2003-01-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.193
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gelsolin precursor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mdua_
  • Chain 'B':
    Compound: a-actin
    Species: Gallus gallus [TaxId:9031]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68139
      • modified residue (74)
    Domains in SCOPe 2.08: d1mdub1, d1mdub2
  • Chain 'D':
    Compound: gelsolin precursor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mdud_
  • Chain 'E':
    Compound: a-actin
    Species: Gallus gallus [TaxId:9031]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68139
      • modified residue (74)
    Domains in SCOPe 2.08: d1mdue1, d1mdue2
  • Heterogens: CA, ATP, TRS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1mduA (A:)
    mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
    lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
    vasgf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mduA (A:)
    vvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydl
    hywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggv
    asgf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1mduB (B:)
    mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
    qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
    mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
    dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
    syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
    msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
    kqeydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mduB (B:)
    ttalvcdngsglvkagfagddapravfpsivgrprgqkdsyvgdeaqskrgiltlkypie
    hgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpam
    yvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmki
    ltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitign
    erfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadr
    mqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivhr
    k
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1mduD (D:)
    mvvehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqyd
    lhywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkgg
    vasgf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mduD (D:)
    vehpeflkagkepglqiwrvekfdlvpvptnlygdfftgdayvilktvqlrngnlqydlh
    ywlgnecsqdesgaaaiftvqlddylngravqhrevqgfesatflgyfksglkykkggva
    sgf
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1mduE (E:)
    mcdedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdea
    qskrgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrek
    mtqimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrl
    dlagrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataasssslek
    syelpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannv
    msggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwit
    kqeydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1mduE (E:)
    ttalvcdngsglvkagfagddapravfpsivgrprhqgqkdsyvgdeaqskrgiltlkyp
    iehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvp
    amyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylm
    kiltergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqviti
    gnerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgia
    drmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsiv
    hr