PDB entry 1mcw
View 1mcw on RCSB PDB site
Description: three-dimensional structure of a hybrid light chain dimer. protein engineering of a binding cavity
Class: immunoglobulin
Keywords: immunoglobulin
Deposited on
1989-05-09, released
1990-10-15
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: 0.17
AEROSPACI score: 0.1
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'M':
Compound: immunoglobulin mcg (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PIR S14675 (1-215)
- conflict (19)
- conflict (22)
- conflict (28)
- conflict (30)
- conflict (38)
- conflict (41)
- conflict (47-48)
- conflict (53)
- conflict (61)
- conflict (93)
- conflict (96-99)
- conflict (102)
- conflict (105-106)
- conflict (115)
- conflict (117)
- conflict (155)
- conflict (166)
Domains in SCOPe 2.03: d1mcwm1, d1mcwm2 - Chain 'W':
Compound: immunoglobulin weir (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PIR S25758 (1-214)
- conflict (19)
- conflict (22)
- conflict (24-25)
- conflict (29-31)
- conflict (33-34)
- conflict (37)
- conflict (42)
- conflict (48)
- conflict (51)
- conflict (54)
- conflict (59-61)
- conflict (80)
- conflict (82)
- conflict (88)
- conflict (90)
- conflict (92-93)
- insertion (95)
- conflict (96)
- conflict (102)
- conflict (107)
- conflict (110)
- conflict (159)
Domains in SCOPe 2.03: d1mcww1, d1mcww2
PDB Chain Sequences:
- Chain 'M':
Sequence; same for both SEQRES and ATOM records: (download)
>1mcwM (M:)
esaltqppsasgslgqsvtisctgtssdvggynyvswyqqhagkapkviiyevnkrpsgv
pdrfsgsksgntasltvsglqaedeadyycssyegsdnfvfgtgtkvtvlgqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs
- Chain 'W':
Sequence; same for both SEQRES and ATOM records: (download)
>1mcwW (W:)
esaltqpasvsgspgqsitvscaghtsdvadsnsiswfqqhpdkapklliyavtfrpsgi
plrfsgsksgntasltisgllpddeadyfcmsylsdasfvfgsgtkvtvlrqpkanptvt
lfppsseelqankatlvclisdfypgavtvawkadgspveagvettkpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptecs