PDB entry 1ma3

View 1ma3 on RCSB PDB site
Description: Structure of a Sir2 enzyme bound to an acetylated p53 peptide
Class: protein binding, transcription
Keywords: enzyme-substrate complex
Deposited on 2002-07-31, released 2002-10-16
The last revision prior to the SCOP 1.73 freeze date was dated 2002-10-16, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.209
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional regulatory protein, Sir2 family
    Species: Archaeoglobus fulgidus
    Gene: SIR2-Af2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ma3a_
  • Chain 'B':
    Compound: Cellular tumor antigen p53
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04637
      • modified residue (10)
  • Heterogens: ZN, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ma3A (A:)
    medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
    rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
    mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
    akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
    kiveevkrlrsek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ma3A (A:)
    medeirkaaeilakskhavvftgagisaeglwrkydpeevasisgfkrnprafwefsmem
    kdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgsmdkldcldch
    etydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaieeakhcdafmvv
    gsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlpkiveevkrlr
    se
    

  • Chain 'B':
    No sequence available.