PDB entry 1m6b

View 1m6b on RCSB PDB site
Description: Structure of the HER3 (ERBB3) Extracellular Domain
Class: signaling protein, transferase
Keywords: tyrosine kinase; cell surface receptor; immunity, SIGNALING PROTEIN, TRANSFERASE
Deposited on 2002-07-15, released 2002-08-02
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.238
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor protein-tyrosine kinase erbB-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21860
      • engineered (60)
    Domains in SCOPe 2.03: d1m6ba1, d1m6ba2, d1m6ba3, d1m6ba4
  • Chain 'B':
    Compound: Receptor protein-tyrosine kinase erbB-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21860
      • engineered (60)
    Domains in SCOPe 2.03: d1m6bb1, d1m6bb2, d1m6bb3, d1m6bb4
  • Heterogens: NAG, NDG, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1m6bA (A:)
sevgnsqavcpgtlnglsvtgdaenqyqtlyklyercevvmgnleivltghnadlsflqw
vrevtgyvlvamnefstlplpnlrvvrgtqvydgkfaifvmlnyntnsshalrqlrltql
teilsggvyiekndklchmdtidwrdivrdrdaeivvkdngrscppchevckgrcwgpgs
edcqtltkticapqcnghcfgpnpnqcchdecaggcsgpqdtdcfacrhfndsgacvprc
pqplvynkltfqlepnphtkyqyggvcvascphnfvvdqtscvracppdkmevdknglkm
cepcgglcpkacegtgsgsrfqtvdssnidgfvnctkilgnldflitglngdpwhkipal
dpeklnvfrtvreitgylniqswpphmhnfsvfsnlttiggrslynrgfsllimknlnvt
slgfrslkeisagriyisanrqlcyhhslnwtkvlrgpteerldikhnrprrdcvaegkv
cdplcssggcwgpgpgqclscrnysrggvcvthcnflngeprefaheaecfschpecqpm
egtatcngsgsdtcaqcahfrdgphcvsscphgvlgakgpiykypdvqnecrpchenctq
gckgpelqdclgqtlvligkt

    Sequence, based on observed residues (ATOM records): (download) 
    >1m6bA (A:)
avcprcevvmgnleivltghnadlsflqwvrevtgyvlvamnefstlplpnlrvvrgtqv
ydgkfaifvmlnyntnsshalrqlrltqlteilsggvyiekndklchmdtidwrdivrdr
daeivvkdngrscppchevckgrcwgpgsedcqtltkticapqcnghcfgpnpnqcchde
caggcsgpqdtdcfacrhfndsgacvprcpqplvynkltfqlepnphtkyqyggvcvasc
phnfvvdqtscvracppdkmevdknglkmcepcgglcpkacegtgsgsrfqtvdssnidg
fvnctkilgnldflitglngdpwhkipaldpeklnvfrtvreitgylniqswpphmhnfs
vfsnlttiggrslynrgfsllimknlnvtslgfrslkeisagriyisanrqlcyhhslnw
tkvlrgpteerldikhnrprrdcvaegkvcdplcssggcwgpgpgqclscrnysrggvcv
thcnflngeprefaheaecfschpecqpmegtatcngsgsdtcaqcahfrdgphcvsscp
hgvlgakgp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1m6bB (B:)
sevgnsqavcpgtlnglsvtgdaenqyqtlyklyercevvmgnleivltghnadlsflqw
vrevtgyvlvamnefstlplpnlrvvrgtqvydgkfaifvmlnyntnsshalrqlrltql
teilsggvyiekndklchmdtidwrdivrdrdaeivvkdngrscppchevckgrcwgpgs
edcqtltkticapqcnghcfgpnpnqcchdecaggcsgpqdtdcfacrhfndsgacvprc
pqplvynkltfqlepnphtkyqyggvcvascphnfvvdqtscvracppdkmevdknglkm
cepcgglcpkacegtgsgsrfqtvdssnidgfvnctkilgnldflitglngdpwhkipal
dpeklnvfrtvreitgylniqswpphmhnfsvfsnlttiggrslynrgfsllimknlnvt
slgfrslkeisagriyisanrqlcyhhslnwtkvlrgpteerldikhnrprrdcvaegkv
cdplcssggcwgpgpgqclscrnysrggvcvthcnflngeprefaheaecfschpecqpm
egtatcngsgsdtcaqcahfrdgphcvsscphgvlgakgpiykypdvqnecrpchenctq
gckgpelqdclgqtlvligkt

    Sequence, based on observed residues (ATOM records): (download) 
    >1m6bB (B:)
sqavcpgtrcevvmgnleivltghnadlsflqwvrevtgyvlvamnefstlplpnlrvvr
gtqvydgkfaifvmlnyntnsshalrqlrltqlteilsggvyiekndklchmdtidwrdi
vrdrdaeivvkdngrscppchevckgrcwgpgsedcqtltkticapqcnghcfgpnpnqc
chdecaggcsgpqdtdcfacrhfndsgacvprcpqplvynkltfqlepnphtkyqyggvc
vascphnfvvdqtscvracppdkmevdknglkmcepcgglcpkacegtgsgsrfqtvdss
nidgfvnctkilgnldflitglngdpwhkipaldpeklnvfrtvreitgylniqswpphm
hnfsvfsnlttiggrslynrgfsllimknlnvtslgfrslkeisagriyisanrqlcyhh
slnwtkvlrgpteerldikhnrprrdcvaegkvcdplcssggcwgpgpgqclscrnysrg
gvcvthcnflngeprefaheaecfschpecqpmegtatcngsgsdtcaqcahfrdgphcv
sscphgvlgakgpiykypdvqnecrpchenctqgckgpelqdcl