PDB entry 1m4u

View 1m4u on RCSB PDB site
Description: Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin
Class: hormone/growth factor
Keywords: noggin, bmp antagonist, bmp-7, bone morphogenetic protein, cystine knot, hormone-growth factor complex
Deposited on 2002-07-03, released 2002-12-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.242
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Noggin
    Species: Homo sapiens [TaxId:9606]
    Gene: NOG
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13253 (1-205)
      • initiating met (0)
    Domains in SCOPe 2.07: d1m4ua_
  • Chain 'L':
    Compound: bone morphogenetic protein-7
    Species: Homo sapiens [TaxId:9606]
    Gene: BMP7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1m4ul_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1m4uA (A:)
mqhylhirpapsdnlplvdliehpdpifdpkekdlnetllrsllgghydpgfmatspped
rpgggggaaggaedlaeldqllrqrpsgampseikglefseglaqgkkqrlskklrrklq
mwlwsqtfcpvlyawndlgsrfwpryvkvgscfskrscsvpegmvckpsksvhltvlrwr
cqrrggqrcgwipiqypiiseckcsc

    Sequence, based on observed residues (ATOM records): (download) 
    >1m4uA (A:)
mqhylhirpapsdnlplvdliehpdpifdpkekdlnetllrsllgghydpgfmatspped
rpggaedlaeldqllrqrpsgampseikglefseglaqgkkqrlskklrrklqmwlwsqt
fcpvlyawndlgsrfwpryvkvgscfskrscsvpegmvckpsksvhltvlrwrcqrrggq
rcgwipiqypiiseckcsc

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1m4uL (L:)
stgskqrsqnrsktpknqealrmanvaensssdqrqackkhelyvsfrdlgwqdwiiape
gyaayycegecafplnsymnatnhaivqtlvhfinpetvpkpccaptqlnaisvlyfdds
snvilkkyrnmvvracgch

    Sequence, based on observed residues (ATOM records): (download) 
    >1m4uL (L:)
ensssdqrqackkhelyvsfrdlgwqdwiiapegyaayycegecafplnsymnatnhaiv
qtlvhfinpetvpkpccaptqlnaisvlyfddssnvilkkyrnmvvracgch