PDB entry 1m16
View 1m16 on RCSB PDB site
Description: Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).
Class: hormone/growth factor
Keywords: beta-trefoil, HORMONE/GROWTH FACTOR COMPLEX
Deposited on
2002-06-17, released
2003-08-05
The last revision prior to the SCOPe 2.07 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.221
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: acidic fibroblast growth factor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P05230 (6-End)
- expression tag (6)
- engineered (49)
- engineered (78)
- engineered (114)
- engineered (122)
- engineered' (122)
Domains in SCOPe 2.07: d1m16a_ - Chain 'B':
Compound: acidic fibroblast growth factor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P05230 (6-End)
- expression tag (6)
- engineered (49)
- engineered (78)
- engineered (114)
- engineered (122)
- engineered' (122)
Domains in SCOPe 2.07: d1m16b_ - Heterogens: SO4, FMT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1m16A (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdglvygsqtpneeclflerleenhyntyiskkhaeknwflglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>1m16A (A:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevy
ikstetgqylamdtdglvygsqtpneeclflerleenhyntyiskkhaeknwflglkkng
svkrgprthygqkailflplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1m16B (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdglvygsqtpneeclflerleenhyntyiskkhaeknwflglkkn
gsvkrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>1m16B (B:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevy
ikstetgqylamdtdglvygsqtpneeclflerleenhyntyiskkhaeknwflglkkng
svkrgprthygqkailflplpv