PDB entry 1m13

View 1m13 on RCSB PDB site
Description: Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort
Class: transcription
Keywords: nuclear receptor, ligand binding domain, protein-ligand complex
Deposited on 2002-06-17, released 2003-03-04
The last revision prior to the SCOP 1.75 freeze date was dated 2003-03-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.212
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orphan nuclear receptor pxr
    Species: HOMO SAPIENS
    Gene: NR1I2 or PXR
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1m13a_
  • Heterogens: HYF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1m13A (A:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1m13A (A:)
glteeqrmmirelmdaqmktfdttfshfknfrlpgvkwsqvrkdlcslkvslqlrgedgs
vwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqisllkgaaf
elcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyv
lmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelr
sinaqhtqrllriqdihpfatplmqelfgitgs