PDB entry 1lya

View 1lya on RCSB PDB site
Description: crystal structures of native and inhibited forms of human cathepsin d: implications for lysosomal targeting and drug design
Deposited on 1993-04-22, released 1994-01-31
The last revision prior to the SCOP 1.67 freeze date was dated 1994-01-31, with a file datestamp of 1994-01-31.
Experiment type: -
Resolution: 2.5 Å
R-factor: 0.188
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Domains in SCOP 1.67: d1lya.1
  • Chain 'B':
    Domains in SCOP 1.67: d1lya.1
  • Chain 'C':
    Domains in SCOP 1.67: d1lya.2
  • Chain 'D':
    Domains in SCOP 1.67: d1lya.2

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lyaA (A:)
gpipevlknymdaqyygeigigtppqcftvvfdtgssnlwvpsihcklldiacwihhkyn
sdksstyvkngtsfdihygsgslsgylsqdtvsvpcq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lyaB (B:)
ggvkverqvfgeatkqpgitfiaakfdgilgmayprisvnnvlpvfdnlmqqklvdqnif
sfylsrdpdaqpggelmlggtdskyykgslsylnvtrkaywqvhldqvevasgltlckeg
ceaivdtgtslmvgpvdevrelqkaigavpliqgeymipcekvstlpaitlklggkgykl
spedytlkvsqagktlclsgfmgmdipppsgplwilgdvfigryytvfdrdnnrvgfaea
a

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lyaC (C:)
gpipevlknymdaqyygeigigtppqcftvvfdtgssnlwvpsihcklldiacwihhkyn
sdksstyvkngtsfdihygsgslsgylsqdtvsvpcq

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1lyaD (D:)
ggvkverqvfgeatkqpgitfiaakfdgilgmayprisvnnvlpvfdnlmqqklvdqnif
sfylsrdpdaqpggelmlggtdskyykgslsylnvtrkaywqvhldqvevasgltlckeg
ceaivdtgtslmvgpvdevrelqkaigavpliqgeymipcekvstlpaitlklggkgykl
spedytlkvsqagktlclsgfmgmdipppsgplwilgdvfigryytvfdrdnnrvgfaea
a