PDB entry 1lx5

View 1lx5 on RCSB PDB site
Description: Crystal Structure of the BMP7/ActRII Extracellular Domain Complex
Class: growth factor/growth factor receptor
Keywords: ligand-receptor complex
Deposited on 2002-06-04, released 2003-04-01
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.24
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: bone morphogenetic protein 7
    Species: HOMO SAPIENS
    Gene: BMP7
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lx5a_
  • Chain 'B':
    Compound: Activin Type II Receptor
    Species: MUS MUSCULUS
    Gene: ACVR2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lx5b_
  • Heterogens: NDG, NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1lx5A (A:)
stgskqrsqnrsktpknqealrmanvaensssdqrqackkhelyvsfrdlgwqdwiiape
gyaayycegecafplnsymnatnhaivqtlvhfinpetvpkpccaptqlnaisvlyfdds
snvilkkyrnmvvracgch

    Sequence, based on observed residues (ATOM records): (download) 
    >1lx5A (A:)
qackkhelyvsfrdlgwqdwiiapegyaayycegecafplnsymnatnhaivqtlvhfin
petvpkpccaptqlnaisvlyfddssnvilkkyrnmvvracgch

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1lx5B (B:)
ailgrsetqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcw
lddincydrtdciekkdspevyfcccegnmcnekfsyfpeme

    Sequence, based on observed residues (ATOM records): (download) 
    >1lx5B (B:)
etqeclffnanwerdrtnqtgvepcygdkdkrrhcfatwknisgsieivkqgcwlddinc
ydrtdciekkdspevyfcccegnmcnekfsyfpe