PDB entry 1lwv

View 1lwv on RCSB PDB site
Description: Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine
Class: hydrolase/DNA
Keywords: DNA repair, DNA glycosylase, protein/DNA, borohydride, covalent trapping, product-assisted catalysis, reaction intermediate, hydrolase/DNA complex
Deposited on 2002-06-03, released 2003-02-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.228
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 8-oxoguanine DNA glycosylase
    Species: Homo sapiens [TaxId:9606]
    Gene: OGG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15527 (8-End)
      • cloning artifact (5-7)
    Domains in SCOPe 2.06: d1lwva1, d1lwva2, d1lwva3
  • Chain 'D':
    Compound: 5'-d(*gp*gp*tp*ap*gp*ap*cp*cp*tp*gp*gp*ap*cp*gp*c)-3'
  • Chain 'E':
    Compound: 5'-d(*gp*cp*gp*tp*cp*cp*ap*(ped)p*gp*tp*cp*tp*ap*cp*c)-3'
  • Heterogens: CA, ANG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1lwvA (A:)
amadigseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqv
wtltqteeqlhctvyrgdksqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqev
aqkfqgvrllrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfps
lqalagpeveahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcil
pgvgtkvadciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnff
rslwgpyagwaqavlfsadlrqsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1lwvA (A:)
gseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrsqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfqgvr
llrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpslqalagpe
veahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgtkva
dciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwgpya
gwaqavlfsadlrq

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.