PDB entry 1lp9

View 1lp9 on RCSB PDB site
Description: Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1
Class: immune system
Keywords: Immunoregulatory complex, Class I MHC:TCR co-crystal, IMMUNE SYSTEM
Deposited on 2002-05-07, released 2003-11-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.221
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A*0201
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lp9a1, d1lp9a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating met (0)
    Domains in SCOPe 2.07: d1lp9b1, d1lp9b2
  • Chain 'C':
    Compound: self-peptide P1049
    Species: synthetic, synthetic
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (0-8)
  • Chain 'E':
    Compound: T-cell receptor alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (0-193)
    Domains in SCOPe 2.07: d1lp9e1, d1lp9e2
  • Chain 'F':
    Compound: T-cell receptor beta chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (Start-237)
    Domains in SCOPe 2.07: d1lp9f1, d1lp9f2
  • Chain 'H':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A*0201
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1lp9h1, d1lp9h2
  • Chain 'I':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating met (0)
    Domains in SCOPe 2.07: d1lp9i1, d1lp9i2
  • Chain 'J':
    Compound: self-peptide P1049
    Species: synthetic, synthetic
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (0-8)
  • Chain 'L':
    Compound: T-cell receptor alpha chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (0-193)
    Domains in SCOPe 2.07: d1lp9l1, d1lp9l2
  • Chain 'M':
    Compound: T-cell receptor beta chain
    Species: Mus musculus [TaxId:10090]
    Gene:
    Database cross-references and differences (RAF-indexed):
    • PDB 1LP9 (Start-237)
    Domains in SCOPe 2.07: d1lp9m1, d1lp9m2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9A (A:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9E (E:)
    mdsvtqteglvtlteglpvmlnctyqstyspflfwyvqhlneapklllksftdnkrpehq
    gfhatlhkssssfhlqkssaqlsdsalyycalflasssfsklvfgqgtslsvvpniqnpe
    pavyqlkdprsqdstlclftdfdsqinvpktmesgtfitdktvldmkamdsksngaiaws
    nqtsftcqdifket
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1lp9F (F:)
    meaavtqsprskvavtggkvtlschqtnnhdymywyrqdtghglrlihysyvadstekgd
    ipdgykasrpsqenfslilelaslsqtavyfcassdwvsyeqyfgpgtrltvledlrnvt
    ppkvslfepskaeiankqkatlvclargffpdhvelswwvngkevhsgvstdpqaykesn
    ysyalssrlrvsatfwhnprnhfrcqvqfhglseedkwpegspkpvtqnisaeawgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1lp9F (F:)
    eaavtqsprskvavtggkvtlschqtnnhdymywyrqdtghglrlihysyvadstekgdi
    pdgykasrpsqenfslilelaslsqtavyfcassdwvsyeqyfgpgtrltvledlrnvtp
    pkvslfepskaeiankqkatlvclargffpdhvelswwvngkevhsgvstdpqaykesny
    syalssrlrvsatfwhnprnhfrcqvqfhglseedkwpegspkpvtqnisaeawgra
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9H (H:)
    gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
    kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
    rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgqeqrytchvqheglpkpltlrwe
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9I (I:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'J':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lp9L (L:)
    mdsvtqteglvtlteglpvmlnctyqstyspflfwyvqhlneapklllksftdnkrpehq
    gfhatlhkssssfhlqkssaqlsdsalyycalflasssfsklvfgqgtslsvvpniqnpe
    pavyqlkdprsqdstlclftdfdsqinvpktmesgtfitdktvldmkamdsksngaiaws
    nqtsftcqdifket
    

  • Chain 'M':
    Sequence, based on SEQRES records: (download)
    >1lp9M (M:)
    meaavtqsprskvavtggkvtlschqtnnhdymywyrqdtghglrlihysyvadstekgd
    ipdgykasrpsqenfslilelaslsqtavyfcassdwvsyeqyfgpgtrltvledlrnvt
    ppkvslfepskaeiankqkatlvclargffpdhvelswwvngkevhsgvstdpqaykesn
    ysyalssrlrvsatfwhnprnhfrcqvqfhglseedkwpegspkpvtqnisaeawgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1lp9M (M:)
    eaavtqsprskvavtggkvtlschqtnnhdymywyrqdtghglrlihysyvadstekgdi
    pdgykasrpsqenfslilelaslsqtavyfcassdwvsyeqyfgpgtrltvledlrnvtp
    pkvslfepskaeiankqkatlvclargffpdhvelswwvngkevhsgvstdpqaykesny
    syalssrlrvsatfwhnprnhfrcqvqfhglseedkwpegspkpvtqnisaeawgra