PDB entry 1lmw

View 1lmw on RCSB PDB site
Description: lmw u-pa structure complexed with egrcmk (glu-gly-arg chloromethyl ketone)
Class: complex (serine protease/inhibitor)
Keywords: fibrinolysis, trypsin-like serine protease
Deposited on 1995-07-26, released 1996-01-29
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.224
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lmw.1
  • Chain 'B':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Domains in SCOP 1.75: d1lmw.1
  • Chain 'C':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lmw.2
  • Chain 'D':
    Compound: urokinase-type plasminogen activator
    Species: HOMO SAPIENS
    Domains in SCOP 1.75: d1lmw.2
  • Chain 'I':
    Compound: glu-gly-arg chloromethyl ketone
  • Chain 'J':
    Compound: glu-gly-arg chloromethyl ketone

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1lmwA (A:)
kpssppeelkfqcgqktlrprfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lmwA (A:)
cgqktlrpr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1lmwB (B:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
clpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkeenglal

    Sequence, based on observed residues (ATOM records): (download) 
    >1lmwB (B:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
clpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkee

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1lmwC (C:)
kpssppeelkfqcgqktlrprfk

    Sequence, based on observed residues (ATOM records): (download) 
    >1lmwC (C:)
cgqktlrp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1lmwD (D:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
clpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkeenglal

    Sequence, based on observed residues (ATOM records): (download) 
    >1lmwD (D:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslmspcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
clpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtkee

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.