PDB entry 1lhf
View 1lhf on RCSB PDB site
Description: human alpha-thrombin complexed with ac-(d)phe-pro-boro-homolys-oh
Class: complex (serine protease/inhibitor)
Keywords: blood coagulation, plasma, calcium-binding, glycoprotein, duplication, vitamin k, zymogen, gamma-carboxyglutamic acid, acute phase, liver, hydrolase, serine protease, kringle, signal, disease mutation, complex (serine protease/inhibitor)
Deposited on
1994-12-27, released
1996-11-08
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.212
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1lhf.1 - Chain 'I':
Compound: hirudin
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: alpha-thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1lhf.1 - Heterogens: DI4, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence, based on SEQRES records: (download)
>1lhfH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1lhfH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
wiqkvidqf
- Chain 'I':
No sequence available.
- Chain 'L':
Sequence, based on SEQRES records: (download)
>1lhfL (L:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1lhfL (L:)
adcglrplfekksledkterellesy