PDB entry 1l7q

View 1l7q on RCSB PDB site
Description: Ser117Ala Mutant of Bacterial Cocaine Esterase cocE
Class: hydrolase
Keywords: beta-alpha-beta, cocaine hydrolase, active site mutant, benzoate product complex
Deposited on 2002-03-16, released 2003-02-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: 0.183
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cocaine esterase
    Species: Rhodococcus sp. MB1 [TaxId:51612]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9L9D7 (Start-573)
      • engineered (116)
    Domains in SCOPe 2.08: d1l7qa1, d1l7qa2
  • Heterogens: BEZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1l7qA (A:)
mvdgnysvasnvmvpmrdgvrlavdlyrpdadgpvpvllvrnpydkfdvfawstqstnwl
efvrdgyavviqdtrglfasegefvphvddeadaedtlswileqawcdgnvgmfgvaylg
vtqwqaavsgvgglkaiapsmasadlyrapwygpggalsveallgwsaligtglitsrsd
arpedaadfvqlaailndvagaasvtplaeqpllgrlipwvidqvvdhpdndeswqsisl
ferlgglatpalitagwydgfvgeslrtfvavkdnadarlvvgpwshsnltgrnadrkfg
iaatypiqeattmhkaffdrhlrgetdalagvpkvrlfvmgidewrdetdwplpdtaytp
fylggsgaantstgggtlstsisgtesadtylydpadpvpslggtllfhngdngpadqrp
ihdrddvlcystevltdpvevtgtvsarlfvsssavdtdftaklvdvfpdgraialcdgi
vrmryretlvnptlieageiyevaidmlatsnvflpghrimvqvsssnfpkydrnsntgg
viareqleemctavnrihrgpehpshivlpiikr

    Sequence, based on observed residues (ATOM records): (download) 
    >1l7qA (A:)
gnysvasnvmvpmrdgvrlavdlyrpdadgpvpvllvrnpydkfdvfawstqstnwlefv
rdgyavviqdtrglfasegefvphvddeadaedtlswileqawcdgnvgmfgvaylgvtq
wqaavsgvgglkaiapsmasadlyrapwygpggalsveallgwsaligtglitsrsdarp
edaadfvqlaailndvagaasvtplaeqpllgrlipwvidqvvdhpdndeswqsislfer
lgglatpalitagwydgfvgeslrtfvavkdnadarlvvgpwshsnltgrnadrkfgiaa
typiqeattmhkaffdrhlrgetdalagvpkvrlfvmgidewrdetdwplpdtaytpfyl
ggsgaantstgggtlstsisgtesadtylydpadpvpslggtllfhngdngpadqrpihd
rddvlcystevltdpvevtgtvsarlfvsssavdtdftaklvdvfpdgraialcdgivrm
ryretlvnptlieageiyevaidmlatsnvflpghrimvqvsssnfpkydrnsntggvia
reqleemctavnrihrgpehpshivlpiikr