PDB entry 1l7i
View 1l7i on RCSB PDB site
Description: Crystal Structure of the anti-ErbB2 Fab2C4
Class: immune system
Keywords: Ig domain, Fab fragment, IMMUNE SYSTEM
Deposited on
2002-03-15, released
2002-07-10
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.197
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: chimera of Fab2C4: "humanized" murine monoclonal antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1l7ih1, d1l7ih2 - Chain 'L':
Compound: chimera of Fab2C4: "humanized" murine monoclonal antibody
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1l7il1, d1l7il2 - Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1l7iH (H:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrqapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1l7iL (L:)
diqmtqspsslsasvgdrvtitckasqdvsigvawyqqkpgkapklliysasyrytgvps
rfsgsgsgtdftltisslqpedfatyycqqyyiypytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec