PDB entry 1kz8

View 1kz8 on RCSB PDB site
Description: crystal structure of porcine fructose-1,6-bisphosphatase complexed with a novel allosteric-site inhibitor
Class: hydrolase
Keywords: hydrolase
Deposited on 2002-02-06, released 2002-10-16
The last revision prior to the SCOP 1.75 freeze date was dated 2002-10-16, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.179
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fructose-1,6-bisphosphatase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636
      • see remark 999 (19)
      • see remark 999 (95)
      • see remark 999 (198)
    Domains in SCOP 1.75: d1kz8a_
  • Chain 'F':
    Compound: fructose-1,6-bisphosphatase
    Species: SUS SCROFA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00636
      • see remark 999 (19)
      • see remark 999 (95)
      • see remark 999 (198)
    Domains in SCOP 1.75: d1kz8f_
  • Heterogens: F6P, MN, AMP, PFE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kz8A (A:)
tdqaafdtnivtltrfvmeqgrkargtgemtqllnslctavkaistavrkagiahlygia
gstnvtgdqvkkldvlsndlvinvlkssfatcvlvteedknaiivepekrgkyvvcfdpl
dgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvng
vncfmldpaigefilvdrnvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapy
garyvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgke
avldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >1kz8A (A:)
nivtltrfvmeqgrkargtgemtqllnslctavkaistavrkagiahlygiagvkkldvl
sndlvinvlkssfatcvlvteedknaiivepekrgkyvvcfdpldgssnidclvsigtif
giyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldpaigefilv
drnvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsmvadvhrtl
vyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivptdihqrapi
ilgspedvtelleiyqkha

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1kz8F (F:)
tdqaafdtnivtltrfvmeqgrkargtgemtqllnslctavkaistavrkagiahlygia
gstnvtgdqvkkldvlsndlvinvlkssfatcvlvteedknaiivepekrgkyvvcfdpl
dgssnidclvsigtifgiyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvng
vncfmldpaigefilvdrnvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapy
garyvgsmvadvhrtlvyggifmypankkspkgklrllyecnpmayvmekagglattgke
avldivptdihqrapiilgspedvtelleiyqkhaak

    Sequence, based on observed residues (ATOM records): (download) 
    >1kz8F (F:)
nivtltrfvmeqgrkargtgemtqllnslctavkaistavrkagiahlygiagvkkldvl
sndlvinvlkssfatcvlvteedknaiivepekrgkyvvcfdpldgssnidclvsigtif
giyrknstdepsekdalqpgrnlvaagyalygsatmlvlamvngvncfmldpaigefilv
drnvkikkkgsiysinegyakefdpaiteyiqrkkfppdnsapygaryvgsmvadvhrtl
vyggifmypankkspkgklrllyecnpmayvmekagglattgkeavldivptdihqrapi
ilgspedvtelleiyqkha