PDB entry 1kyo

View 1kyo on RCSB PDB site
Description: yeast cytochrome bc1 complex with bound substrate cytochrome c
Class: oxidoreductase/electron transport
Keywords: multisubunit membrane protein complex, enzyme substrate complex, electron transfer complex, antibody Fv fragment mediated crystallization, OXIDOREDUCTASE/ELECTRON TRANSPORT COMPLEX
Deposited on 2002-02-05, released 2002-03-06
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.97 Å
R-factor: 0.229
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquinol-cytochrome c reductase complex core protein I
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07256 (0-429)
      • conflict (125)
    Domains in SCOPe 2.05: d1kyoa1, d1kyoa2
  • Chain 'B':
    Compound: ubiquinol-cytochrome c reductase complex core protein 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyob1, d1kyob2
  • Chain 'C':
    Compound: cytochrome b
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00163 (0-384)
      • see remark 999 (269)
    Domains in SCOPe 2.05: d1kyoc2, d1kyoc3
  • Chain 'D':
    Compound: cytochrome c1, heme protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyod1, d1kyod2
  • Chain 'E':
    Compound: ubiquinol-cytochrome c reductase iron-sulfur subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyoe1, d1kyoe2
  • Chain 'F':
    Compound: ubiquinol-cytochrome c reductase complex 17 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00127 (0-73)
      • conflict (0)
    Domains in SCOPe 2.05: d1kyof_
  • Chain 'G':
    Compound: ubiquinol-cytochrome c reductase complex 14 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyog_
  • Chain 'H':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyoh_
  • Chain 'I':
    Compound: ubiquinol-cytochrome c reductase complex 7.3 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22289
      • conflict (53)
    Domains in SCOPe 2.05: d1kyoi_
  • Chain 'J':
    Compound: heavy chain (vh) of fv-fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1KYO (0-126)
    Domains in SCOPe 2.05: d1kyoj_
  • Chain 'K':
    Compound: light chain (vl) of fv-fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1KYO (0-106)
    Domains in SCOPe 2.05: d1kyok_
  • Chain 'L':
    Compound: ubiquinol-cytochrome c reductase complex core protein I
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07256 (0-429)
      • conflict (125)
    Domains in SCOPe 2.05: d1kyol1, d1kyol2
  • Chain 'M':
    Compound: ubiquinol-cytochrome c reductase complex core protein 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyom1, d1kyom2
  • Chain 'N':
    Compound: cytochrome b
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00163 (0-384)
      • see remark 999 (269)
    Domains in SCOPe 2.05: d1kyon2, d1kyon3
  • Chain 'O':
    Compound: cytochrome c1, heme protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyoo1, d1kyoo2
  • Chain 'P':
    Compound: ubiquinol-cytochrome c reductase iron-sulfur subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyop1, d1kyop2
  • Chain 'Q':
    Compound: ubiquinol-cytochrome c reductase complex 17 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00127 (0-73)
      • conflict (0)
    Domains in SCOPe 2.05: d1kyoq_
  • Chain 'R':
    Compound: ubiquinol-cytochrome c reductase complex 14 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyor_
  • Chain 'S':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1kyos_
  • Chain 'T':
    Compound: ubiquinol-cytochrome c reductase complex 7.3 kd protein
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22289
      • conflict (53)
    Domains in SCOPe 2.05: d1kyot_
  • Chain 'U':
    Compound: heavy chain (vh) of fv-fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1KYO (0-126)
    Domains in SCOPe 2.05: d1kyou_
  • Chain 'V':
    Compound: light chain (vl) of fv-fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1KYO (0-106)
    Domains in SCOPe 2.05: d1kyov_
  • Chain 'W':
    Compound: cytochrome c, iso-1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00044 (0-107)
      • modified residue (76)
    Domains in SCOPe 2.05: d1kyow_
  • Heterogens: HEM, FES, SMA

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoA (A:)
    aevtqlsngivvatehnpahtasvgvvfgsgaanenpynngvsnlwkniflskensavaa
    keglalssnisrdfqsyivsslpgstdksldflnqsfiqqkanllsssnfeatkksvlkq
    vqdfedndhpnrvlehlhstafqntplslptrgtleslenlvvadlesfannhflnsnav
    vvgtgnikhedlvnsiesknlslqtgtkpvlkkkaaflgsevrlrddtlpkawislaveg
    epvnspnyfvaklaaqifgsynafepasrlqgiklldniqeyqlcdnfnhfslsykdsgl
    wgfstatrnvtmiddlihftlkqwnrltisvtdteveraksllklqlgqlyesgnpvnda
    nllgaevlikgsklslgeafkkidaitvkdvkawagkrlwdqdiaiagtgqieglldymr
    irsdmsmmrw
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoB (B:)
    ltvsardaptkistlavkvhggsryatkdgvahllnrfnfqntntrsalklvresellgg
    tfkstldreyitlkatflkddlpyyvnaladvlyktafkpheltesvlpaarydyavaeq
    cpvksaedqlyaitfrkglgnpllydgvervslqdikdfadkvytkenlevsgenvvead
    lkrfvdesllstlpagkslvsksepkfflgeenrvrfigdsvaaigipvnkaslaqyevl
    anyltsalselsglissakldkftdgglftlfvrdqdsavvssnikkivadlkkgkdlsp
    ainytklknavqnesvsspielnfdavkdfklgkfnyvavgdvsnlpyldel
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoC (C:)
    mafrksnvylslvnsyiidspqpssinywwnmgsllglclviqivtgifmamhyssniel
    afssvehimrdvhngyilrylhangasfffmvmfmhmakglyygsyrsprvtlwnvgvii
    ftltiataflgyccvygqmshwgatvitnlfsaipfvgndivswlwggfsvsnptiqrff
    alhylvpfiiaamvimhlmalhihgssnplgitgnldripmhsyfifkdlvtvflfmlil
    alfvfyspntlghpdnyipgnplvtpasivpewyllpfyailrsipdkllgvitmfaail
    vllvlpftdrsvvrgntfkvlskffffifvfnfvllgqigachvevpyvlmgqiatfiyf
    ayfliivpvistienvlfyigrvnk
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1kyoD (D:)
    mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
    neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
    karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
    attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
    fnppkprk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoD (D:)
    mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
    neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
    karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
    attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
    fnppk
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoE (E:)
    kstyrtpnfddvlkenndadkgrsyayfmvgamgllssagakstvetfissmtatadvla
    makvevnlaaiplgknvvvkwqgkpvfirhrtpheiqeansvdmsalkdpqtdadrvkdp
    qwlimlgicthlgcvpigeagdfggwfcpchgshydisgrirkgpaplnleipayefdgd
    kvivg
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoF (F:)
    dtdqledlrehfknteegkalvhhyeecaervkiqqqqpgyadlehkedcveeffhlqhy
    ldtataprlfdklk
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1kyoG (G:)
    pqsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalr
    rlpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeld
    nievsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoG (G:)
    qsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalrr
    lpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeldn
    ievsk
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoH (H:)
    gppsgktymgwwghmggpkqkgitsyavspyaqkplqgifhnavfnsfrrfksqflyvli
    pagiywywwkngneyneflyskagreelervnv
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1kyoI (I:)
    sfsslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkakiaa
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoI (I:)
    sslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkaki
    

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoJ (J:)
    evklqesgaglvqpsqslsltcsvtgysitsgyywnwirlfpgnklewvgyisnvgdnny
    npslkdrlsitrdtsknqfflklnsvttedtatyycarseyysvtgyamdywgqgttvtv
    ssawrhp
    

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoK (K:)
    dieltqtpvslaaslgdrvtiscrasqdinnflnwyqqkpdgtiklliyytsrlhagvps
    rfsgsgsgtdysltisnlepediatyfcqhhikfpwtfgagtkleik
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoL (L:)
    aevtqlsngivvatehnpahtasvgvvfgsgaanenpynngvsnlwkniflskensavaa
    keglalssnisrdfqsyivsslpgstdksldflnqsfiqqkanllsssnfeatkksvlkq
    vqdfedndhpnrvlehlhstafqntplslptrgtleslenlvvadlesfannhflnsnav
    vvgtgnikhedlvnsiesknlslqtgtkpvlkkkaaflgsevrlrddtlpkawislaveg
    epvnspnyfvaklaaqifgsynafepasrlqgiklldniqeyqlcdnfnhfslsykdsgl
    wgfstatrnvtmiddlihftlkqwnrltisvtdteveraksllklqlgqlyesgnpvnda
    nllgaevlikgsklslgeafkkidaitvkdvkawagkrlwdqdiaiagtgqieglldymr
    irsdmsmmrw
    

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoM (M:)
    ltvsardaptkistlavkvhggsryatkdgvahllnrfnfqntntrsalklvresellgg
    tfkstldreyitlkatflkddlpyyvnaladvlyktafkpheltesvlpaarydyavaeq
    cpvksaedqlyaitfrkglgnpllydgvervslqdikdfadkvytkenlevsgenvvead
    lkrfvdesllstlpagkslvsksepkfflgeenrvrfigdsvaaigipvnkaslaqyevl
    anyltsalselsglissakldkftdgglftlfvrdqdsavvssnikkivadlkkgkdlsp
    ainytklknavqnesvsspielnfdavkdfklgkfnyvavgdvsnlpyldel
    

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoN (N:)
    mafrksnvylslvnsyiidspqpssinywwnmgsllglclviqivtgifmamhyssniel
    afssvehimrdvhngyilrylhangasfffmvmfmhmakglyygsyrsprvtlwnvgvii
    ftltiataflgyccvygqmshwgatvitnlfsaipfvgndivswlwggfsvsnptiqrff
    alhylvpfiiaamvimhlmalhihgssnplgitgnldripmhsyfifkdlvtvflfmlil
    alfvfyspntlghpdnyipgnplvtpasivpewyllpfyailrsipdkllgvitmfaail
    vllvlpftdrsvvrgntfkvlskffffifvfnfvllgqigachvevpyvlmgqiatfiyf
    ayfliivpvistienvlfyigrvnk
    

  • Chain 'O':
    Sequence, based on SEQRES records: (download)
    >1kyoO (O:)
    mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
    neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
    karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
    attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
    fnppkprk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoO (O:)
    mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
    neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
    karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
    attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
    fnppk
    

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoP (P:)
    kstyrtpnfddvlkenndadkgrsyayfmvgamgllssagakstvetfissmtatadvla
    makvevnlaaiplgknvvvkwqgkpvfirhrtpheiqeansvdmsalkdpqtdadrvkdp
    qwlimlgicthlgcvpigeagdfggwfcpchgshydisgrirkgpaplnleipayefdgd
    kvivg
    

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoQ (Q:)
    dtdqledlrehfknteegkalvhhyeecaervkiqqqqpgyadlehkedcveeffhlqhy
    ldtataprlfdklk
    

  • Chain 'R':
    Sequence, based on SEQRES records: (download)
    >1kyoR (R:)
    pqsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalr
    rlpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeld
    nievsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoR (R:)
    qsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalrr
    lpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeldn
    ievsk
    

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoS (S:)
    gppsgktymgwwghmggpkqkgitsyavspyaqkplqgifhnavfnsfrrfksqflyvli
    pagiywywwkngneyneflyskagreelervnv
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >1kyoT (T:)
    sfsslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkakiaa
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kyoT (T:)
    sslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkaki
    

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoU (U:)
    evklqesgaglvqpsqslsltcsvtgysitsgyywnwirlfpgnklewvgyisnvgdnny
    npslkdrlsitrdtsknqfflklnsvttedtatyycarseyysvtgyamdywgqgttvtv
    ssawrhp
    

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoV (V:)
    dieltqtpvslaaslgdrvtiscrasqdinnflnwyqqkpdgtiklliyytsrlhagvps
    rfsgsgsgtdysltisnlepediatyfcqhhikfpwtfgagtkleik
    

  • Chain 'W':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kyoW (W:)
    tefkagsakkgatlfktrclqchtvekggphkvgpnlhgifgrhsgqaegysytdanikk
    nvlwdennmseyltnpkkyipgtkmafgglkkekdrndlitylkkace