PDB entry 1kyo

View 1kyo on RCSB PDB site
Description: yeast cytochrome bc1 complex with bound substrate cytochrome c
Class: oxidoreductase/electron transport
Keywords: multisubunit membrane protein complex, enzyme substrate complex, electron transfer complex, antibody Fv fragment mediated crystallization
Deposited on 2002-02-05, released 2002-03-06
The last revision prior to the SCOP 1.75 freeze date was dated 2002-03-06, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.97 Å
R-factor: 0.229
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquinol-cytochrome c reductase complex core protein I
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07256 (0-429)
      • conflict (125)
    Domains in SCOP 1.75: d1kyoa1, d1kyoa2
  • Chain 'B':
    Compound: ubiquinol-cytochrome c reductase complex core protein 2
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyob1, d1kyob2
  • Chain 'C':
    Compound: cytochrome b
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00163 (0-384)
      • see remark 999 (269)
    Domains in SCOP 1.75: d1kyoc2, d1kyoc3
  • Chain 'D':
    Compound: cytochrome c1, heme protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyod1, d1kyod2
  • Chain 'E':
    Compound: ubiquinol-cytochrome c reductase iron-sulfur subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyoe1, d1kyoe2
  • Chain 'F':
    Compound: ubiquinol-cytochrome c reductase complex 17 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00127 (0-73)
      • conflict (0)
    Domains in SCOP 1.75: d1kyof_
  • Chain 'G':
    Compound: ubiquinol-cytochrome c reductase complex 14 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyog_
  • Chain 'H':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyoh_
  • Chain 'I':
    Compound: ubiquinol-cytochrome c reductase complex 7.3 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22289
      • conflict (53)
    Domains in SCOP 1.75: d1kyoi_
  • Chain 'J':
    Compound: heavy chain (vh) of fv-fragment
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1kyoj_
  • Chain 'K':
    Compound: light chain (vl) of fv-fragment
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1kyok_
  • Chain 'L':
    Compound: ubiquinol-cytochrome c reductase complex core protein I
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07256 (0-429)
      • conflict (125)
    Domains in SCOP 1.75: d1kyol1, d1kyol2
  • Chain 'M':
    Compound: ubiquinol-cytochrome c reductase complex core protein 2
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyom1, d1kyom2
  • Chain 'N':
    Compound: cytochrome b
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00163 (0-384)
      • see remark 999 (269)
    Domains in SCOP 1.75: d1kyon2, d1kyon3
  • Chain 'O':
    Compound: cytochrome c1, heme protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyoo1, d1kyoo2
  • Chain 'P':
    Compound: ubiquinol-cytochrome c reductase iron-sulfur subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyop1, d1kyop2
  • Chain 'Q':
    Compound: ubiquinol-cytochrome c reductase complex 17 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00127 (0-73)
      • conflict (0)
    Domains in SCOP 1.75: d1kyoq_
  • Chain 'R':
    Compound: ubiquinol-cytochrome c reductase complex 14 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyor_
  • Chain 'S':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1kyos_
  • Chain 'T':
    Compound: ubiquinol-cytochrome c reductase complex 7.3 kd protein
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22289
      • conflict (53)
    Domains in SCOP 1.75: d1kyot_
  • Chain 'U':
    Compound: heavy chain (vh) of fv-fragment
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1kyou_
  • Chain 'V':
    Compound: light chain (vl) of fv-fragment
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1kyov_
  • Chain 'W':
    Compound: cytochrome c, iso-1
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00044 (0-107)
      • modified residue (76)
    Domains in SCOP 1.75: d1kyow_
  • Heterogens: HEM, FES, SMA

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoA (A:)
aevtqlsngivvatehnpahtasvgvvfgsgaanenpynngvsnlwkniflskensavaa
keglalssnisrdfqsyivsslpgstdksldflnqsfiqqkanllsssnfeatkksvlkq
vqdfedndhpnrvlehlhstafqntplslptrgtleslenlvvadlesfannhflnsnav
vvgtgnikhedlvnsiesknlslqtgtkpvlkkkaaflgsevrlrddtlpkawislaveg
epvnspnyfvaklaaqifgsynafepasrlqgiklldniqeyqlcdnfnhfslsykdsgl
wgfstatrnvtmiddlihftlkqwnrltisvtdteveraksllklqlgqlyesgnpvnda
nllgaevlikgsklslgeafkkidaitvkdvkawagkrlwdqdiaiagtgqieglldymr
irsdmsmmrw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoB (B:)
ltvsardaptkistlavkvhggsryatkdgvahllnrfnfqntntrsalklvresellgg
tfkstldreyitlkatflkddlpyyvnaladvlyktafkpheltesvlpaarydyavaeq
cpvksaedqlyaitfrkglgnpllydgvervslqdikdfadkvytkenlevsgenvvead
lkrfvdesllstlpagkslvsksepkfflgeenrvrfigdsvaaigipvnkaslaqyevl
anyltsalselsglissakldkftdgglftlfvrdqdsavvssnikkivadlkkgkdlsp
ainytklknavqnesvsspielnfdavkdfklgkfnyvavgdvsnlpyldel

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoC (C:)
mafrksnvylslvnsyiidspqpssinywwnmgsllglclviqivtgifmamhyssniel
afssvehimrdvhngyilrylhangasfffmvmfmhmakglyygsyrsprvtlwnvgvii
ftltiataflgyccvygqmshwgatvitnlfsaipfvgndivswlwggfsvsnptiqrff
alhylvpfiiaamvimhlmalhihgssnplgitgnldripmhsyfifkdlvtvflfmlil
alfvfyspntlghpdnyipgnplvtpasivpewyllpfyailrsipdkllgvitmfaail
vllvlpftdrsvvrgntfkvlskffffifvfnfvllgqigachvevpyvlmgqiatfiyf
ayfliivpvistienvlfyigrvnk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1kyoD (D:)
mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
fnppkprk

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoD (D:)
mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
fnppk

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoE (E:)
kstyrtpnfddvlkenndadkgrsyayfmvgamgllssagakstvetfissmtatadvla
makvevnlaaiplgknvvvkwqgkpvfirhrtpheiqeansvdmsalkdpqtdadrvkdp
qwlimlgicthlgcvpigeagdfggwfcpchgshydisgrirkgpaplnleipayefdgd
kvivg

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoF (F:)
dtdqledlrehfknteegkalvhhyeecaervkiqqqqpgyadlehkedcveeffhlqhy
ldtataprlfdklk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1kyoG (G:)
pqsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalr
rlpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeld
nievsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoG (G:)
qsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalrr
lpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeldn
ievsk

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoH (H:)
gppsgktymgwwghmggpkqkgitsyavspyaqkplqgifhnavfnsfrrfksqflyvli
pagiywywwkngneyneflyskagreelervnv

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1kyoI (I:)
sfsslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkakiaa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoI (I:)
sslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkaki

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoJ (J:)
evklqesgaglvqpsqslsltcsvtgysitsgyywnwirlfpgnklewvgyisnvgdnny
npslkdrlsitrdtsknqfflklnsvttedtatyycarseyysvtgyamdywgqgttvtv
ssawrhp

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoK (K:)
dieltqtpvslaaslgdrvtiscrasqdinnflnwyqqkpdgtiklliyytsrlhagvps
rfsgsgsgtdysltisnlepediatyfcqhhikfpwtfgagtkleik

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoL (L:)
aevtqlsngivvatehnpahtasvgvvfgsgaanenpynngvsnlwkniflskensavaa
keglalssnisrdfqsyivsslpgstdksldflnqsfiqqkanllsssnfeatkksvlkq
vqdfedndhpnrvlehlhstafqntplslptrgtleslenlvvadlesfannhflnsnav
vvgtgnikhedlvnsiesknlslqtgtkpvlkkkaaflgsevrlrddtlpkawislaveg
epvnspnyfvaklaaqifgsynafepasrlqgiklldniqeyqlcdnfnhfslsykdsgl
wgfstatrnvtmiddlihftlkqwnrltisvtdteveraksllklqlgqlyesgnpvnda
nllgaevlikgsklslgeafkkidaitvkdvkawagkrlwdqdiaiagtgqieglldymr
irsdmsmmrw

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoM (M:)
ltvsardaptkistlavkvhggsryatkdgvahllnrfnfqntntrsalklvresellgg
tfkstldreyitlkatflkddlpyyvnaladvlyktafkpheltesvlpaarydyavaeq
cpvksaedqlyaitfrkglgnpllydgvervslqdikdfadkvytkenlevsgenvvead
lkrfvdesllstlpagkslvsksepkfflgeenrvrfigdsvaaigipvnkaslaqyevl
anyltsalselsglissakldkftdgglftlfvrdqdsavvssnikkivadlkkgkdlsp
ainytklknavqnesvsspielnfdavkdfklgkfnyvavgdvsnlpyldel

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoN (N:)
mafrksnvylslvnsyiidspqpssinywwnmgsllglclviqivtgifmamhyssniel
afssvehimrdvhngyilrylhangasfffmvmfmhmakglyygsyrsprvtlwnvgvii
ftltiataflgyccvygqmshwgatvitnlfsaipfvgndivswlwggfsvsnptiqrff
alhylvpfiiaamvimhlmalhihgssnplgitgnldripmhsyfifkdlvtvflfmlil
alfvfyspntlghpdnyipgnplvtpasivpewyllpfyailrsipdkllgvitmfaail
vllvlpftdrsvvrgntfkvlskffffifvfnfvllgqigachvevpyvlmgqiatfiyf
ayfliivpvistienvlfyigrvnk

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >1kyoO (O:)
mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
fnppkprk

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoO (O:)
mtaaehglhapayawshngpfetfdhasirrgyqvyrevcaachsldrvawrtlvgvsht
neevrnmaeefeyddepdeqgnpkkrpgklsdyipgpypneqaaraanqgalppdlsliv
karhggcdyifslltgypdeppagvalppgsnynpyfpggsiamarvlfddmveyedgtp
attsqmakdvttflnwcaepehderkrlglktviilsslyllsiwvkkfkwagiktrkfv
fnppk

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoP (P:)
kstyrtpnfddvlkenndadkgrsyayfmvgamgllssagakstvetfissmtatadvla
makvevnlaaiplgknvvvkwqgkpvfirhrtpheiqeansvdmsalkdpqtdadrvkdp
qwlimlgicthlgcvpigeagdfggwfcpchgshydisgrirkgpaplnleipayefdgd
kvivg

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoQ (Q:)
dtdqledlrehfknteegkalvhhyeecaervkiqqqqpgyadlehkedcveeffhlqhy
ldtataprlfdklk

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >1kyoR (R:)
pqsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalr
rlpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeld
nievsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoR (R:)
qsftsiarigdyilkspvlsklcvpvanqfinlagykklglkfddliaeenpimqtalrr
lpedesyarayriirahqtelthhllprnewikaqedvpyllpyileaeaaakekdeldn
ievsk

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoS (S:)
gppsgktymgwwghmggpkqkgitsyavspyaqkplqgifhnavfnsfrrfksqflyvli
pagiywywwkngneyneflyskagreelervnv

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >1kyoT (T:)
sfsslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkakiaa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kyoT (T:)
sslyktffkrnavfvgtifagafvfqtvfdtaitswyenhnkgklwkdvkaki

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoU (U:)
evklqesgaglvqpsqslsltcsvtgysitsgyywnwirlfpgnklewvgyisnvgdnny
npslkdrlsitrdtsknqfflklnsvttedtatyycarseyysvtgyamdywgqgttvtv
ssawrhp

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoV (V:)
dieltqtpvslaaslgdrvtiscrasqdinnflnwyqqkpdgtiklliyytsrlhagvps
rfsgsgsgtdysltisnlepediatyfcqhhikfpwtfgagtkleik

  • Chain 'W':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kyoW (W:)
tefkagsakkgatlfktrclqchtvekggphkvgpnlhgifgrhsgqaegysytdanikk
nvlwdennmseyltnpkkyipgtkmafgglkkekdrndlitylkkace