PDB entry 1kvk

View 1kvk on RCSB PDB site
Description: The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
Class: transferase
Keywords: rmk, ATP, ghmp, transferase
Deposited on 2002-01-26, released 2002-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mevalonate Kinase
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1kvka1, d1kvka2
  • Heterogens: MG, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1kvkA (A:)
    mlsevllvsapgkvilhgehavvhgkvalavalnlrtflvlrpqsngkvslnlpnvgikq
    vwdvatlqlldtgfleqgdvpaptleqleklkkvaglprdcvgneglsllaflylylaic
    rkqrtlpsldimvwselppgaglgssaaysvcvaaalltaceevtnplkdrgsigswpee
    dlksinkwayegervihgnpsgvdnsvstwggalryqqgkmsslkrlpalqilltntkvp
    rstkalvagvrsrlikfpeimaplltsidaislecervlgemaaapvpeqylvleelmdm
    nqhhlnalgvghasldqlcqvtaahglhskltgaggggcgitllkpglerakveaakqal
    tgcgfdcwetsigapgvsmhsatsiedpvrqalgl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kvkA (A:)
    mlsevllvsapgkvilhgehavvhgkvalavalnlrtflvlrpqsngkvslnlpnvgikq
    vwdvatlqlldteklkkvaglprdcvgneglsllaflylylaicrkqrtlpsldimvwse
    lppgaglgssaaysvcvaaalltaceevtnplkdrgsigswpeedlksinkwayegervi
    hgnpsgvdnsvstwggalryqqgkmsslkrlpalqilltntkvprstkalvagvrsrlik
    fpeimaplltsidaislecervlgemaaapvpeqylvleelmdmnqhhlnalgvghasld
    qlcqvtaahglhskltgaggggcgitllkpglerakveaakqaltgcgfdcwetsigapg
    vsmhsatsiedpvrqalg