PDB entry 1kv3

View 1kv3 on RCSB PDB site
Description: human tissue transglutaminase in GDP bound form
Class: transferase
Keywords: tissue transglutaminase; GTP binding protein; crystallography, TRANSFERASE
Deposited on 2002-01-24, released 2002-03-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.233
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3a1, d1kv3a2, d1kv3a3, d1kv3a4
  • Chain 'B':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3b1, d1kv3b2, d1kv3b3, d1kv3b4
  • Chain 'C':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3c1, d1kv3c2, d1kv3c3, d1kv3c4
  • Chain 'D':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3d1, d1kv3d2, d1kv3d3, d1kv3d4
  • Chain 'E':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3e1, d1kv3e2, d1kv3e3, d1kv3e4
  • Chain 'F':
    Compound: protein-glutamine gamma-glutamyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21980 (Start-686)
      • see remark 999 (185)
      • see remark 999 (223)
      • see remark 999 (532)
      • see remark 999 (654)
    Domains in SCOPe 2.07: d1kv3f1, d1kv3f2, d1kv3f3, d1kv3f4
  • Heterogens: GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kv3A (A:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3A (A:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kv3B (B:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3B (B:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1kv3C (C:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3C (C:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1kv3D (D:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3D (D:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1kv3E (E:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3E (E:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1kv3F (F:)
maeelvlercdleletngrdhhtadlcreklvvrrgqpfwltlhfegrnyqasvdsltfs
vvtgpapsqeagtkarfplrdaveegdwtatvvdqqdctlslqlttpanapiglyrlsle
astgyqgssfvlghfillfnawcpadavyldseeerqeyvltqqgfiyqgsakfiknipw
nfgqfqdgildiclilldvnpkflknagrdcsrrsspvyvgrvgsgmvncnddqgvllgr
wdnnygdgvspmswigsvdilrrwknhgcqrvkygqcwvfaavactvlrclgiptrvvtn
ynsahdqnsnllieyfrnefgeiqgdksemiwnfhcwveswmtrpdlqpgyegwqaldpt
pqeksegtyccgpvpvraikegdlstkydapfvfaevnadvvdwiqqddgsvhksinrsl
ivglkistksvgrderedithtykypegsseereaftranhlnklaekeetgmamrirvg
qsmnmgsdfdvfahitnntaeeyvcrlllcartvsyngilgpecgtkyllnltlepfsek
svplcilyekyrdcltesnlikvrallvepvinsyllaerdlylenpeikirilgepkqk
rklvaevslqnplpvalegctftvegaglteeqktveipdpveageevkvrmdlvplhmg
lhklvvnfesdklkavkgfrnviigpa

    Sequence, based on observed residues (ATOM records): (download) 
    >1kv3F (F:)
etngrdhhtadlcreklvvrrgqpfwltlsltfsvvtgpapsqeagtkarfplrdaveeg
dwtatvvdqqdctlslqlttpanapiglyrlsleasghfillfnawcpadavyldseeer
qeyvltqqgfiyqgsakfiknipwnfgqfqdgildiclilldvnpkflknagrdcsrrss
pvyvgrvgsgmvncnddqgvllgrwdnnygdgvspmswigsvdilrrwknhgcqrvkygq
cwvfaavactvlrclgiptrvvtnynsahdqnsnllieyfrnefgeiqgdksemiwnfhc
wveswmtrpdlqpgyegwqaldptpqeksegtyccgpvpvraikegdlstkydapfvfae
vnadvvdwiqqddgsvhksinrslivglkistksvgrderedithtykypegsseereaf
tranhlnklaekeetgmamrirvgqsmnmgsdfdvfahitnntaeeyvcrlllcartvsy
ngilgpecgtkyllnltlepfseksvplcilyekyrdcltesnlikvrallvepvinsyl
laerdlylenpeikirilgepkqkrklvaevslqnplpvalegctftvegaglteeqktv
eipdpveageevkvrmdlvplhmglhklvvnfesdklkavkgfrnviigpa