PDB entry 1kps

View 1kps on RCSB PDB site
Description: Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1
Class: ligase/protein transport
Keywords: sumo, ubiquitin, e2, conjugating enzyme, ligase, thioester, small ubiquitin-like modifier
Deposited on 2002-01-02, released 2002-02-13
The last revision prior to the SCOP 1.73 freeze date was dated 2002-02-13, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-like protein SUMO-1 conjugating enzyme
    Species: HOMO SAPIENS
    Gene: UBC9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63279 (1-158)
      • cloning artifact (0)
    Domains in SCOP 1.73: d1kpsa_
  • Chain 'B':
    Compound: Ran-GTPase activating protein 1
    Species: MUS MUSCULUS
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1kpsb_
  • Chain 'C':
    Compound: Ubiquitin-like protein SUMO-1 conjugating enzyme
    Species: HOMO SAPIENS
    Gene: UBC9
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1kpsc_
  • Chain 'D':
    Compound: Ran-GTPase activating protein 1
    Species: MUS MUSCULUS
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1kpsd_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1kpsA (A:)
    smsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfk
    lrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqel
    lnepniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1kpsB (B:)
    snsgepapvlssptptdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkv
    asvfrddasvktavldaidalmkkafscssfnsntfltrllihmgllksedkikaipslh
    gplmvlnhvvrqdyfpkalaplllafvtkpngaletcsfarhnllqtlyni
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kpsB (B:)
    tdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkvasvfrddasvktavl
    daidalmkkafscssfnsntfltrllihmgllksedkikaipslhgplmvlnhvvrqdyf
    pkalaplllafvtkpngaletcsfarhnllqtlyni
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1kpsC (C:)
    smsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfk
    lrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqel
    lnepniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kpsC (C:)
    gialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklrm
    lfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqellne
    pniqdpaqaeaytiycqnrveyekrvraqakkfaps
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1kpsD (D:)
    snsgepapvlssptptdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkv
    asvfrddasvktavldaidalmkkafscssfnsntfltrllihmgllksedkikaipslh
    gplmvlnhvvrqdyfpkalaplllafvtkpngaletcsfarhnllqtlyni
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kpsD (D:)
    dlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkvasvfrddasvktavld
    aidalmkkafscssfnsntfltrllihmgllksedkikaipslhgplmvlnhvvrqdyfp
    kalaplllafvtkpngaletcsfarhnllqtlyni